Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 508019
Title Molecular, genetic and evolutionary analysis of a paracentric inversion in Arabidopsis thaliana
Author(s) Fransz, Paul; Linc, Gabriella; Lee, Cheng Ruei; Aflitos, Saulo Alves; Lasky, Jesse R.; Toomajian, Christopher; Ali, Hoda; Peters, Janny; Dam, Peter van; Ji, Xianwen; Kuzak, Mateusz; Gerats, Tom; Schubert, Ingo; Schneeberger, Korbinian; Colot, Vincent; Martienssen, Rob; Koornneef, Maarten; Nordborg, Magnus; Juenger, Thomas E.; Jong, Hans de; Schranz, Eric
Source The Plant Journal 88 (2016)2. - ISSN 0960-7412 - p. 159 - 178.
Department(s) PRI BIOS Applied Bioinformatics
Groep KoornneefGroep Koornneef
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Arabidopsis thaliana - Chromosome rearrangement - Haplotype pattern - Introgression - Phylogenetic relationship - Transposon

Chromosomal inversions can provide windows onto the cytogenetic, molecular, evolutionary and demographic histories of a species. Here we investigate a paracentric 1.17-Mb inversion on chromosome 4 of Arabidopsis thaliana with nucleotide precision of its borders. The inversion is created by Vandal transposon activity, splitting an F-box and relocating a pericentric heterochromatin segment in juxtaposition with euchromatin without affecting the epigenetic landscape. Examination of the RegMap panel and the 1001 Arabidopsis genomes revealed more than 170 inversion accessions in Europe and North America. The SNP patterns revealed historical recombinations from which we infer diverse haplotype patterns, ancient introgression events and phylogenetic relationships. We find a robust association between the inversion and fecundity under drought. We also find linkage disequilibrium between the inverted region and the early flowering Col-FRIGIDA allele. Finally, SNP analysis elucidates the origin of the inversion to South-Eastern Europe approximately 5000 years ago and the FRI-Col allele to North-West Europe, and reveals the spreading of a single haplotype to North America during the 17th to 19th century. The 'American haplotype' was identified from several European localities, potentially due to return migration.

There are no comments yet. You can post the first one!
Post a comment
Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.