Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 508126
Title Accumulation of persistent organic pollutants in consumers of eel from polluted rivers compared to marketable eel
Author(s) Dungen, Myrthe W. van den; Gils-Kok, Dieuwertje van; Polder, Anuschka; Hoogenboom, R.L.A.P.; Leeuwen, S.P.J. van; Steegenga, Wilma T.; Kampman, Ellen; Murk, Albertinka J.
Source Environmental Pollution 219 (2016). - ISSN 0269-7491 - p. 80 - 88.
DOI http://dx.doi.org/10.1016/j.envpol.2016.09.019
Department(s) Sub-department of Environmental Technology
Chair Nutrition and Disease
VLAG
RIKILT - BU Toxicology Bioassays & Novel Foods
RIKILT - Business unit Contaminants & Toxins
Chair Nutrition Metabolism and Genomics
Marine Animal Ecology
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Consumer health - Dioxins - eel (Anguilla anguilla) - Hydroxylated PCBs - Persistent organic pollutants (POPs) - PFOS
Abstract

Globally, many river sediments are seriously contaminated with persistent organic pollutants (POPs) known to accumulate in aquatic food. In the Netherlands, toxicological risks of human exposure to dioxins and dioxin-like compounds led to a ban on eel fishing in the Rhine-Meuse delta. The aim of this study is to investigate differences in serum POP levels in consumers of eel from high-polluted areas and consumers of eel from low-polluted areas or aquaculture. In total 80 Dutch men were included, aged 40–70 years, with a habitual eel consumption of at least one portion (150 g) per month. Total levels of dioxins and dioxin-like compounds were measured in serum of all participants with the DR CALUX bioassay, validated with GC-MS. For a subgroup of 38 participants extensive POP measurements were performed. We revealed that consumption of eel from polluted rivers resulted in 2.5 and up to 10 times increased levels of dioxins and polychlorinated biphenyls (PCBs) respectively compared to controls. The highest PCB levels were detected for PCB 153, with a median level of 896 ng/g lipid and a maximum level of 5000 ng/g lipid in the high-exposed group. Furthermore, hydroxylated PCB metabolites (OH-PCBs: sum of 4-OH-CB107, 4-OH-CB146, 4′-OH-CB172, and 4-OH-CB187) were 8 times higher in men who consumed eel from polluted areas, and detected at levels (median 4.5 ng/g ww) reported to cause adverse health effects. Also, the majority of the perfluoroalkyl substances (PFASs) were significantly higher in consumers of eel from pullulated areas. In conclusion, this study is the first to reveal that (past) consumption of eel from polluted rivers resulted in high body burdens of dioxins, PCBs, OH-PCBs and PFASs. We confirmed the predictions made in a former risk assessment, and the high levels of dioxins and dioxin-like compounds as well as the OH-PCBs are of health concern.

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