Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 510225
Title Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach
Author(s) Alajlouni, Abdul; Al-Malahmeh, Amer J.; Isnaeni, Farida Nur; Wesseling, Sebas; Vervoort, Jacques; Rietjens, Ivonne M.C.M.
Source Journal of Agricultural and Food Chemistry 64 (2016)45. - ISSN 0021-8561 - p. 8640 - 8646.
DOI http://dx.doi.org/10.1021/acs.jafc.6b03650
Department(s) Sub-department of Toxicology
Biochemistry
VLAG
WIMEK
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) alkenylbenzenes - estimated daily intake - margin of exposure - parsley and dill based teas - risk assessment - toxic equivalency factors
Abstract

Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene, a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called toxic equivalency (TEQ) approach through defining toxic equivalency factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0.2-10.1 μg/kg bw for the individual alkenylbenzenes, 0.6-13.1 μg/kg bw for the sum of the alkenylbenzenes, and 0.3-10.7 μg safrole equiv/kg bw for the sum of alkenylbenzenes when expressed in safrole equivalents. The margin of exposure (MOE) values obtained were generally

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