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Record number 520456
Title HDG1 transcription factor targets
Author(s) Horstman, A.; Boutilier, K.A.; Sanchez Perez, Gabino
Department(s) PRI BIOS Plant Development Systems
EPS
PRI BIOS Applied Bioinformatics
Bioinformatics
Publication type Dataset
Publication year 2015
Keyword(s) Arabidopsis thaliana - GSE54312 - PRJNA236137
Abstract The AIL transcription factor BABY BOOM (BBM) is required together with the related PLETHORA proteins for embryo and root meristem development and its expression is sufficient to confer pluripotency and totipotency to somatic tissues. We show that BBM and other AIL proteins interact with multiple members of the L1/epidermal-expressed HD-ZIP class IV / HOMEODOMAIN GLABROUS (HDG) transcription factor family. Ectopic overexpression of HDG1, HDG11 and HDG12 genes induces a reduced growth phenotype, and analysis of HDG1 overexpression lines shows that this growth reduction is due to both root and shoot meristem arrest. To understand how HDG1 controls cell proliferation, as well as its functional relationship with BBM, we performed microarray experiments to identify candidate genes that are directly regulated by HDG1, and compared these to the set of genes that are directly regulated by BBM expression.
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