Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 525209
Title Comprehensive DNA methylation and gene expression profiling in differentiating human adipocytes
Author(s) Dungen, Myrthe van den; Murk, Tinka; Gils-Kok, Dieuwertje van; Steegenga, Wilma
Department(s) Sub-department of Environmental Technology
Marine Animal Ecology
Chair Nutrition and Disease
VLAG
Chair Nutrition Metabolism and Genomics
Publication type Dataset
Publication year 2016
Keyword(s) GSE74609 - Homo sapiens - PRJNA300955
Abstract Genome-wide DNA methylation profiling was performed of human mesenchymal stem cells (hMSCs) differentiating into adipocytes (day 10). The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to measure DNA methylation of hMSC before differentiation (day 0) and of adipocytes at day 10 of differentiation. Our aims were to 1) measure genome-wide DNA methylation changes during adipocyte differentiation in primary hMSCs and 2) investigate the relationship between DNA methylation and gene expression regulation in a panel of 84 adipocyte-related genes.
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