Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 529842
Title Nutritional effects by beta-carotene in liver in males and females of control wildtype mice versus BCMO knockout mice
Author(s) Schothorst, E.M. van; Helden, Y.G.J.; Keijer, J.; Hessel, S.; Bunschoten, J.E.; Lintig, J. von; Lietz, G.
Department(s) Human and Animal Physiology
Publication type Dataset
Publication year 2017
Keyword(s) Mus musculus - GSE98846 - PRJNA386384
Abstract Molecular mechanisms triggered by high dietary beta-carotene (BC) intake in liver are largely unknown. We performed microarray gene expression analysis on liver tissue of BC supplemented beta-carotene 15,150-monooxygenase 1 knockout (Bcmo1-/-) mice, which are—like humans—able to accumulate BC. This was compared with litter mates being wild-type (Bcmo1+/+) mice, and we analysed both males and females, as we previously showed that in lung tissue we observed opposite gene regulation between males and females.
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