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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

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Record number 530341
Title Genetic Admixture in Indigenous Ugandan goat breeds using genome-wide SNP data
Author(s) Onzima, Robert; Upadhyay, M.R.; Mukiibi, Robert; Kanis, E.; Crooijmans, R.P.M.A.
Source In: Abstract Book 36th conference of the International Society of Animal Genetics (ISAG). - ISAG - p. 193 - 194.
Event 36th conference of the International Society of Animal Genetics (ISAG), Dublin, 2017-07-16/2017-07-21
Department(s) Animal Breeding and Genetics
WIAS
Publication type Abstract in scientific journal or proceedings
Publication year 2017
Abstract Well-adapted indigenous goats are an important genetic resource for future sustainable production in marginal areas. The introduction of exotic Boer goats for meat production in Uganda has had an effect on the diversity of the goat genetic resources in the country. Little is known about the effect of exotic Boer goats on the genetic diversity and population structure of the goat breeds in Uganda. The objective of this study was therefore to assess genetic admixture and population structure in goat population in Uganda. Five indigenous Ugandan goats of Mubende (n = 29), Kigezi (n = 29), Small East African (n = 29), Sebei (n = 29) and Karamojong (n = 15) and exotic Boer (n = 13) were assessed using caprine SNP50 bead chip. The polymorphism (MAF >0.05) across the breeds was 93.4% with the highest polymorphism observed in Sebei (92.8%) and lowest in Kigezi (88.5%). The average heterozygosity across the populations was (0.384 ± 0.143) with the lowest heterozygosity recorded in Kigezi (0.377 ± 0.189) and the highest in Karamojong (0.410 ± 0.192). Principle component analysis (PCA) and ADMIXTURE analysis inferred Boer as an outlier population from the Ugandan indigenous goat breeds, whereas ADMIXTURE clustered Ugandan indigenous goat populations into Small East African and two indistinct clusters of Kigezi & Mubende and Karamojong & Sebei. These clusters may reflect the similarity of the breeds by ancestry separated by distance.. Admixture analysis and four population tests further revealed introgression of the Boer into indigenous animals. Information derived from the level of admixture will be useful in maintaining genetic diversity and designing appropriate breeding programs to exploit within breed selection and heterotic advantage in cross-breeding schemes.
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