Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 535930
Title Vector competence of European mosquitoes for west Nile virus
Author(s) Vogels, Chantal B.F.; Göertz, Giel P.; Pijlman, Gorben P.; Koenraadt, Constantianus J.M.
Source Emerging Microbes and Infections 6 (2017)11. - ISSN 2222-1751
DOI https://doi.org/10.1038/emi.2017.82
Department(s) Laboratory of Entomology
PE&RC
Laboratory of Virology
Publication type Refereed Article in a scientific journal
Publication year 2017
Keyword(s) Europe - Innate immune responses - Midgut barrier - Mosquito - Salivary gland barrier - Surveillance - Vector competence - West nile virus
Abstract West Nile virus (WNV) is an arthropod-borne flavivirus of high medical and veterinary importance. The main vectors for WNV are mosquito species of the Culex genus that transmit WNV among birds, and occasionally to humans and horses, which are 'deadend' hosts. Recently, several studies have been published that aimed to identify the mosquito species that serve as vectors for WNV in Europe. These studies provide insight in factors that can influence vector competence of European mosquito species for WNV. Here, we review the current knowledge on vector competence of European mosquitoes for WNV, and the molecular knowledge on physical barriers, anti-viral pathways and microbes that influence vector competence based on studies with other flaviviruses. By comparing the 12 available WNV vector competence studies with European mosquitoes we evaluate the effect of factors such as temperature, mosquito origin and mosquito biotype on vector competence. In addition, we propose a standardised methodology to allow for comparative studies across Europe. Finally, we identify knowledge gaps regarding vector competence that, once addressed, will provide important insights into WNV transmission and ultimately contribute to effective strategies to control WNV.
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