Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 537882
Title Emulsion encapsulation in calcium-alginate beads delays lipolysis during dynamic in vitro digestion
Author(s) Corstens, M.N.; Berton-Carabin, C.C.; Schroen, C.G.P.H.; Viau, Michele; Meynier, Anne
Source Journal of Functional Foods 46 (2018). - ISSN 1756-4646 - p. 394 - 402.
DOI https://doi.org/10.1016/j.jff.2018.05.011
Department(s) Food Process Engineering
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2018
Abstract We assessed the behaviour of encapsulated oil-in-water emulsions in alginate beads under dynamic digestion conditions to test their suitability for ileal brake activation. A dynamic gastrointestinal digestion system (DIDGI) was used with three consecutive compartments simulating the stomach, duodenum and distal small intestine. Digestive media were collected periodically to follow lipolysis, as well as the solubilisation of absorbable lipid species in mixed micelles. Free emulsions (i.e., non-encapsulated) in absence or presence of empty alginate beads were used as controls. In the free emulsions lipolysis occurred rapidly with micellar solubilisation not rate limiting, which indicates proximal digestion and absorption. Encapsulation of emulsions in calcium-alginate beads delayed lipolysis typically for 3 h by diffusion limitation, after which most probably mechanical disintegration took place. Our findings do not only increase the understanding of the dynamics of lipid digestion, but also directly link to the design of encapsulates (size and mesh size) for long-term weight management strategies.
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