Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 540971
Title Pharmaceuticals and endocrine disruptors in raw and cooked seafood from European market : Concentrations and human exposure levels
Author(s) Álvarez-Muñoz, Diana; Rodríguez-Mozaz, Sara; Jacobs, Silke; Serra-Compte, Albert; Cáceres, Nuria; Sioen, Isabelle; Verbeke, Wim; Barbosa, Vera; Ferrari, Federico; Fernández-Tejedor, Margarita; Cunha, Sara; Granby, Kit; Robbens, Johan; Kotterman, Michiel; Marques, Antonio; Barceló, Damià
Source Environment International 119 (2018). - ISSN 0160-4120 - p. 570 - 581.
DOI https://doi.org/10.1016/j.envint.2018.07.006
Department(s) CS Internet/IntranetInternet/Intranet
RIKILT - BU Authenticity & Nutrients
IMARES Onderzoeksformatie
Publication type Refereed Article in a scientific journal
Publication year 2018
Keyword(s) Cooking - Dietary exposure - Endocrine disruptors - Pharmaceuticals - Risk - Seafood
Abstract

Pharmaceuticals (PhACs) and endocrine disrupting compounds (EDCs) are chemicals of emerging concern that can accumulate in seafood sold in markets. These compounds may represent a risk to consumers through effects on the human reproductive system, metabolic disorders, pathogenesis of breast cancer or development of microbial resistance. Measuring their levels in highly consumed seafood is important to assess the potential risks to human health. Besides, the effect of cooking on contaminant levels is relevant to investigate. Therefore, the objectives of this research were to study the presence and levels of PhACs and EDCs in commercially available seafood in the European Union market, to investigate the effect of cooking on contaminant levels, and to evaluate the dietary exposure of humans to these compounds through seafood consumption. A sampling survey of seafood from 11 European countries was undertaken. Twelve highly consumed seafood types were analysed raw and cooked with 3 analytical methods (65 samples, 195 analysis). PhACs were mostly not detectable or below quantification limits in seafood whereas EDCs were a recurrent group of contaminants quantified in the majority of the samples. Besides, cooking by steaming significantly increased their levels in seafood from 2 to 46-fold increase. Based on occurrence and levels, bisphenol A, methylparaben and triclosan were selected for performing a human exposure assessment and health risk characterisation through seafood consumption. The results indicate that the Spanish population has the highest exposure to the selected EDCs through seafood consumption, although the exposure via seafood remained below the current toxicological reference values.

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