Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 541466
Title Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis
Author(s) Rogier, Rebecca; Ederveen, Thomas H.A.; Boekhorst, Jos; Wopereis, H.J.; Scher, Jose U.; Manasson, Julia; Knol, J.; Garssen, Johan; Kraan, Peter M. van der; Koenders, Marije I.; Berg, Wim B. van den; Hijum, Sacha A.F.T. van; Abdollahi-Roodsaz, Shahla
Department(s) Microbiological Laboratory
Publication type Dataset
Publication year 2014
Keyword(s) PRJEB7447 - ERP007176
Abstract The aim of this study was to investigate the role of IL-1 receptor signalling and the involvement of Toll-like receptor (TLR) 2 and TLR4 in defining the intestinal microbiota and the associated mucosal and systemic immune response. Multiplex 454 pyrosequencing of V5 and V6 hyper-variable regions of fecal bacterial 16S rRNA was used to define intestinal microbial communities in BALB/c wild type (WT), IL-1Ra-/- and IL-1Ra/TLR double knock-out (DKO) mice.
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