Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 541637
Title Process for producing itaconic acid under anaerobic conditions
Author(s) Weusthuis, R.A.; Vuoristo, K.S.; Eggink, G.; Sanders, J.P.M.
Source Octrooinummer: WO2016131818, verleend: 2016-08-25.
Department(s) Bioprocess Engineering
FBR Bioconversion
Biobased Products
Publication type Patent
Publication year 2016
Abstract The present invention relates to a method for the production of itaconic acid, which method comprises fermenting a recombinant cell capable of producing itaconic acid in a suitable fermentation medium, thereby to produce itaconic acid, wherein: (a) the recombinant cell: (i) overexpresses cis-aconitate decarboxylase; and (ii) overexpresses a part of the citric acid cycle and/or has reduced activity of a native metabolic route to acetate and/or lactate; and, optionally, (b) the fermentation is carried out under anaerobic conditions.
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