Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 545116
Title Renaissance of traditional DNA transfer strategies for improvement of industrial lactic acid bacteria
Author(s) Bron, Peter A.; Marcelli, Barbara; Mulder, Joyce; Els, Simon van der; Morawska, Luiza P.; Kuipers, Oscar P.; Kok, Jan; Kleerebezem, Michiel
Source Current Opinion in Biotechnology 56 (2019). - ISSN 0958-1669 - p. 61 - 68.
DOI https://doi.org/10.1016/j.copbio.2018.09.004
Department(s) Host Microbe Interactomics
WIAS
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2019
Abstract

The ever-expanding genomic insight in natural diversity of lactic acid bacteria (LAB) has revived the industrial interest in traditional and natural genetic mobilization methodologies. Here, we review recent advances in horizontal gene transfer processes in LAB, including natural competence, conjugation, and phage transduction. In addition, we envision the possibilities for industrial strain improvement arising from the recent discoveries of molecular exchanges between bacteria through nanotubes and extracellular vesicles, as well as the constantly expanding genome editing possibilities using the CRISPR-Cas technology.

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