Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 545505
Title Quality of dietary fat intake and body weight and obesity in a mediterranean population : Secondary analyses within the PREDIMED trial
Author(s) Beulen, Yvette; Martínez-González, Miguel A.; Rest, Ondine van de; Salas-Salvadó, Jordi; Sorlí, José V.; Gómez-Gracia, Enrique; Fiol, Miquel; Estruch, Ramón; Santos-Lozano, José M.; Schröder, Helmut; Alonso-Gómez, Angel; Serra-Majem, Luis; Pintó, Xavier; Ros, Emilio; Becerra-Tomas, Nerea; González, José I.; Fitó, Montserrat; Martínez, J.A.; Gea, Alfredo
Source Nutrients 10 (2018)12. - ISSN 2072-6643
Department(s) Health and Society
Chair Nutrition and Health over the Lifecourse
Publication type Refereed Article in a scientific journal
Publication year 2018
Keyword(s) Body weight - Cohort study - Fat - Obesity - Substitution models

A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yearly repeated validated food-frequency questionnaires, and anthropometric outcomes (median follow-up: 4.8 years). The effects of replacing dietary fat subtypes for one another, proteins or carbohydrates were estimated using generalized estimating equations substitution models. Replacement of 5% energy from saturated fatty acids (SFA) with monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids (PUFA) resulted in weight changes of −0.38 kg (95% Confidece Iinterval (CI): −0.69, −0.07), and −0.51 kg (95% CI: −0.81, −0.20), respectively. Replacing proteins with MUFA or PUFA decreased the odds of becoming obese. Estimates for the daily substitution of one portion of red meat with white meat, oily fish or white fish showed weight changes up to −0.87 kg. Increasing the intake of unsaturated fatty acids at the expense of SFA, proteins, and carbohydrates showed beneficial effects on body weight and obesity. It may therefore be desirable to encourage high-quality fat diets like the Mediterranean diet instead of restricting total fat intake.

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