Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 63673
Title Interactions between the immune system and the hypothalamo-pituitary-interrenal axis in fish
Author(s) Weyts, F.A.A.; Cohen, N.; Flik, G.; Verburg-van Kemenade, B.M.L.
Source Fish and Shellfish Immunology 9 (1999). - ISSN 1050-4648 - p. 1 - 20.
Department(s) Cell Biology and Immunology
Publication type Refereed Article in a scientific journal
Publication year 1999
Abstract Endocrine-immune interaction in mammals is realized through a bi-directional communication network functioning through shared receptors and signal molecules to ensure physiological homeostasis. Maintenance of physio-logical homeostasis in a changing and challenging environment is pivotal to the survival of every organism. This review summarises knowledge on immune-endocrine interactions in fish, with focus on the central role of the hypothalamo-pituitary-interrenal axis. Teleosts have well-developed immune and endocrine systems that require communication to realize homeostasis. The head kidney of fish takes a particular place in the study of immune-endocrine interactions. It combines in one organ key-features of both systems: haematopoiesis, antibody production and cortisol and catecholamine production. The head kidney, therefore, offers the opportunity for direct paracrine communication between the immune and endocrine systems in a specific microenvironment. We consider this interaction of relevance durig basal conditions as well as during situations of stress.
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