Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 64104
Title Fruits and vegetables increase plasma carotenoids and vitamins and decrease homocysteine in humans
Author(s) Broekmans, W.M.R.; Klöpping-Ketelaars, I.A.A.; Schuurman, R.R.W.C.; Verhagen, H.; Berg, H. van den; Kok, F.J.; Poppel, G. van
Source The Journal of Nutrition 130 (2000). - ISSN 0022-3166 - p. 1578 - 1583.
Department(s) Human Nutrition (HNE)
Publication type Refereed Article in a scientific journal
Publication year 2000
Abstract Observational epidemiologic studies have shown that a high consumption of fruits and vegetables is associated with a decreased risk of chronic diseases. Little is known about the bioavailability of constituents from vegetables and fruits and the effect of these constituents on markers for disease risk. Currently, the recommendation is to increase intake of a mix of fruits and vegetables ("five a day"). We investigated the effect of this recommendation on plasma carotenoids, vitamins and homocysteine concentrations in a 4-wk dietary controlled, parallel intervention study. Male and female volunteers (n = 47) were allocated randomly to either a daily 500-g fruit and vegetable ("high") diet or a 100-g fruit and vegetable ("low") diet. Analyzed total carotenoid, vitamin C and folate concentrations of the daily high diet were 13.3 mg, 173 mg and 228.1 ?g, respectively. The daily low diet contained 2.9 mg carotenoids, 65 mg vitamin C and 131.1 ?g folate. Differences in final plasma levels between the high and low group were as follows: lutein, 46$95␌onfidence interval (CI) 28–64]; ß-cryptoxanthin, 128ø98–159); lycopene, 22ø8–37); -carotene, 121ø94–149); ß-carotene, 45ø28–62); and vitamin C, 64ø51–77) (P < 0.05). The high group had an 11ø-18 to -4) lower final plasma homocysteine and a 15ø0.8–30) higher plasma folate concentration compared with the low group (P < 0.05). This is the first trial to show that a mix of fruits and vegetables, with a moderate folate content, decreases plasma homocysteine concentrations in humans.
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