Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 65696
Title Introduction, persistence and fade-out of porcine reproductive and respiratory syndrome virus in a Dutch breeding herd : a mathematical analysis
Author(s) Nodelijk, G.; Jong, M.C.M. de; Nes, A. van; Vernooij, J.C.M.; Leengoed, L.A.M.G.; Pol, J.M.A.; Verheijden, J.H.M.
Source Epidemiology and Infection 124 (2000)1. - ISSN 0950-2688 - p. 173 - 182.
Department(s) ID Lelystad, Institute for Animal Science and Health
Quantitative Veterinary Epidemiology
Publication type Refereed Article in a scientific journal
Publication year 2000
Abstract The objective of this study was to investigate the dynamics of PRRSV infection and to quantify transmission within a breeding herd, and its impact on herd performance. For this purpose a longitudinal study was performed in a closed breeding herd of 115 sows. Statistical methods and Monte Carlo simulations based on stochastic SIR models were used to analyse the observational data. Moreover, a case-control study was performed to determine whether seroconversion of sows during gestation was associated with aberrant litters. The transmission parameter R was estimated to be 3.0 (95% confidence interval 1.5-6.0) for the model version based on the most plausible assumptions that the infectious period lasts 56 days and no lifelong immunity exists after infection. Based on simulations using a breeding herd of equal size the average time-to-extinction was estimated to be 6 years; using a herd of twice the size, it was 80 years. Furthermore, in contrast to the epidemic phase of the disease, the endemic phase was not detrimental to herd performance.
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