- I.A. Brouwer (1)
- E.M. Brouwer (1)
- T.J.M. Cammen van der (1)
- R. Campos (2)
- R.A.M. Dhonukshe-Rutten (2)
- S.C. Dijk van (1)
- A. Enneman (5)
- A. Geelen (1)
- C.P.G.M. Groot de (2)
- A.C. Ham (1)
- L. Hernandez (2)
- E. Kampman (1)
- P. Lips (2)
- A.V. Palma (1)
- G.K. Pot (1)
- G.T. Rijkers (1)
- N.M. Schoor van (2)
- Y.M. Smulders (1)
- N.W. Solomons (2)
- K. Swart (1)
- K.M.A. Swart (1)
- A.G. Uitterlinden (1)
- N. Velde van der (1)
- M. Vossenaar (2)
- J.P. Wijngaarden van (2)
- N.L. Zwaluw van der (1)
The effect of B-vitamin supplementation on arterial stiffness in elderly. The B-Proof trial
Dijk, S.C. van; Smulders, Y.M. ; Enneman, A. ; Swart, K.M.A. ; Wijngaarden, J.P. van; Ham, A.C. ; Zwaluw, N.L. van der; Brouwer, E.M. ; Schoor, N.M. van; Dhonukshe-Rutten, R.A.M. ; Groot, C.P.G.M. de; Lips, P. ; Uitterlinden, A.G. - \ 2013
European Geriatric Medicine 4 (2013)Suppl. 1. - ISSN 1878-7649 - p. S133 - S133.
Contribution of complementary foods to the total daily water needs of urban Guatemalan infants
Enneman, A. ; Campos, R. ; Hernandez, L. ; Palma, A.V. ; Vossenaar, M. ; Solomons, N.W. - \ 2010
Journal of Human Nutrition and Dietetics 23 (2010)5. - ISSN 0952-3871 - p. 520 - 528.
milk intake - nutrient - inadequate - toddlers - quality - maize
Background: Estimates of adequate intake (AI) for water only became available in 2005. The daily water AI for 6-12-month-old infants of both sexes is 800 mL. The present study aimed to estimate the water intake of urban infants receiving both breast milk and complementary feeding (CF) and to compare them with the reference AI. Methods: Sixty-four infants, 42 boys and 22 girls, aged 6-12 months on enrolment, from a low-income district of Guatemala City, were recruited to the study. Quantitative 24-h recalls and breastfeeding histories were collected in three serial interviews. The quantity of water was estimated from recipes and food composition moisture values for the CF items reported. The amount of breast milk needed to complement foods and beverages in meeting the individual energy needs was calculated, and breast milk's water contribution was derived accordingly. The total quantity of water in beverages, including human milk, liquids in recipes and moisture of foods, was tabulated as the infants' daily intake. Results: Some 56.3% of the water needs for boys and 41.1% for girls were satisfied by just water obtained from plain water, other complementary beverages and moisture of foods within CF, exclusive of breast milk. Adding the estimated breast milk intake, the median water intake for the infant sample was essentially equal to the 800 mL of the AI. Conclusions: The infants in this low-income community are approximating the recommended AI for daily water through the currently selected pattern of lactation and CF.
|B-PROOF: B-vitamins for the prevention of osteoporotic fractures, a randomized placebo-controlled double-blind trial
Wijngaarden, J.P. van; Dhonukshe-Rutten, R.A.M. ; Schoor, N.M. van; Velde, N. van der; Swart, K. ; Enneman, A. ; Cammen, T.J.M. van der; Lips, P. ; Groot, C.P.G.M. de - \ 2010
Journal of Nutrition, Health and Aging 14 (2010)6. - ISSN 1279-7707 - p. 501 - 501.
Introduction: Current observational evidence strongly suggests that B-vitamins play a role in the prevention of fractures. Poor vitamin B12 and folate status contribute largely to homocysteine elevation. It is hypothesized that supplementation with these B-vitamins will reduce fracture incidence in elderly people. Objective: To determine the effect of vitamin B12 and folic acid supplementation on fracture incidence in hyperhomocysteinemic elderly people, in a double-blind, placebo-controlled trial. Methods: The B-PROOF (B-Vitamins for the Prevention Of Osteoporotic Fractures) study is a randomized double-blind placebocontrolled trial. The intervention comprises a period of two years, and aims for the inclusion of 3000 subjects, aged 65 years and older, free living and institutionalized, with elevated homocysteine levels (=12µmol/L). One group receives a tablet with 500 µg vitamin B12 and 400 µg folic acid daily and the other group receives a placebo tablet. In both tablets 15 µg (600 IE) of vitamin D is included. Measurements are performed at baseline and after two years and cover bone health, physical activity and functioning, cognitive function, nutritional intake and status, depression and quality of life. This large multi-center project is carried out by a consortium from the Erasmus MC (Rotterdam), VUmc (Amsterdam) and Wageningen University, acting as coordinator. Relevance: It is of major importance to prevent osteoporosis from entering the clinical state, preferably through non-invasive interventions, such as ensuring adequate nutrient intakes, i.e. vitamin B12 and folic acid. Because of the high prevalence of elevated homocysteine levels (10%- 50%) in the elderly population, many elderly may benefit from possibly beneficial effects emerging from this trial, reduce their risk of fracture and improve their health status in a relative simple way, once implementation strategies are applied.
Dietary characteristics of complementary foods offered to Guatemalan infants vary between urban and rural settings
Enneman, A. ; Hernandez, L. ; Campos, R. ; Vossenaar, M. ; Solomons, N.W. - \ 2009
Nutrition Research 29 (2009)7. - ISSN 0271-5317 - p. 470 - 479.
quality - diversity - children - variety - adequacy - patterns - nutrition - scores - index - maize
The objective of this study was to describe and compare the dietary variety, diversity, and origins of complementary foods given to urban and rural Guatemalan infants in the second semester of life. Dietary intake from a total of 128 infants of both sexes, aged 6.0 to 12.0 months on admission, from a low-income district of Guatemala City and a rural Mayan village was collected by means of 3 nonconsecutive 24-hour quantitative intake recalls and breast-feeding histories. We hypothesized that rural/urban, age, and sex differences would occur with respect to dietary variety and diversity scores and descriptive features at 7 levels, that is, animal or plant origin (animal, plant, both, or water); solids or semisolids vs soups and stews vs, liquids; infant vs family foods; modem vs traditional foods; processed vs nonprocessed foods; commercial vs noncommercial foods; and fortified vs nonfortified foods. Overall dietary variety and diversity scores did not differ significantly between sampling areas or between sexes. Infants aged 9 to 12 months had a higher dietary variety and diversity than infants aged 6 to 9 months. Plant sources constituted a large part of the diet in both areas. Foods prepared specifically for infants, rather than for the household, were not common, although more common in the urban area than in the rural area. Commercial, processed, and fortified foods were commonly consumed in both settings. It can be concluded that although no geographical differences were seen in dietary variety or diversity, distinctions between types of selected and consumed foods were observed.
No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals
Pot, G.K. ; Brouwer, I.A. ; Enneman, A. ; Rijkers, G.T. ; Kampman, E. ; Geelen, A. - \ 2009
European Journal of Clinical Nutrition 63 (2009)11. - ISSN 0954-3007 - p. 1353 - 1359.
polyunsaturated fatty-acids - long-chain n-3 - physical-activity scale - adhesion molecules - dietary supplementation - eicosapentaenoic acid - cytokine production - human monocytes - elderly pase - plasma
Background: A high intake of n-3 polyunsaturated fatty acids (PUFAs), mainly present in fish, may be associated with decreased inflammation. Previous intervention studies on fish PUFA and inflammatory markers in healthy individuals did not analyze a broad spectrum of inflammatory cytokines, chemokines and cell adhesion molecules, or their interrelationships. Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals. Methods: Individuals (n=77) aged 50–70 years completed a randomized, double-blind placebo-controlled intervention study. Participants received 3.5 g/day fish oil (1.5 g/day total n-3 PUFA) (n=39) or placebo (high oleic sunflower oil) (n=38) for 12 weeks. Serum concentrations of 19 inflammatory markers were determined using a multiplex immunoassay before and after intervention. Changes in concentrations were analyzed using analysis of covariance and differences in patterns in inflammatory markers between the fish oil and placebo group were analyzed by principal component analysis. Results: Fish oil supplementation did not significantly affect serum concentrations of cytokines, chemokines or cell adhesion molecules as compared with placebo. However, there was a trend for all inflammatory markers to increase after fish oil supplementation. PCA did not result in markedly distinctive patterns of inflammatory markers for the fish oil and placebo group. Conclusion: In conclusion, this 12-week randomized, double-blind placebo-controlled intervention trial did not show that 1.5 g/day n-3 PUFA significantly affected the serum inflammatory response in healthy individuals, nor did patterns of inflammatory markers. Thus, a healthy middle-aged population may not benefit from fish oil as an anti-inflammatory agent