Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Psychosocial correlates of the motivation to abstain from sexual intercourse among Indonesian adolescents
Leerlooijer, J.N. ; Ruiter, R.A.C. ; Damayanti, R. ; Rijsdijk, E. ; Eiling, E. ; Bos, A.E.R. ; Kok, G. - \ 2014
Tropical Medicine and International Health 19 (2014)1. - ISSN 1360-2276 - p. 74 - 82.
planned behavior - hiv prevention - condom use - predictors - model - intentions - metaanalysis - attitudes - efficacy - students
ObjectivesAdolescents in Indonesia have limited access to sexuality education, resulting in increased risk of sexually transmitted infections and unplanned pregnancies. This study aimed to understand psychosocial correlates of sexual abstinence intentions to inform future sexuality education. MethodsData were collected in 79 secondary schools among 2315 students, aged 14-20years, in Jambi, Lampung, Jakarta and Bali. A self-completed questionnaire measured attitudes, risk perception, subjective norms, perceived behavioural control and intentions towards sexual abstinence. ResultsSignificant associations with intention to abstain from sexual intercourse were found for experience with sexual intercourse, perceived behavioural control, attitude and subjective norms of peers and parents, explaining 31% of the variance in abstinence intention. ConclusionsTo promote adolescents' informed sexual decision-making, sexuality education programmes in Indonesia may benefit from addressing past sexual behaviour and perceived behavioural control, subjective norms of peers and attitudes.
Maternal and paternal infant representations: A comparison between parents of term and preterm infants
Tooten, A. ; Hall, R.A.S. ; Hoffenkamp, H.N. ; Braeken, J. ; Vingerhoets, A.J.J.M. ; Bakel, H.J.A. van - \ 2014
Infant Behavior and Development 37 (2014)3. - ISSN 0163-6383 - p. 366 - 379.
disorganized attachment - early-childhood - insightfulness - birth - preschoolers - metaanalysis - narratives - resolution - behavior - emotion
Objective: Research on parental attachment representations after preterm birth is limited and inconclusive. The present study is the first in which maternal and paternal attachment representations after term, moderately and very preterm birth are compared. In addition, special attention was directed toward disrupted attachment representations. Method: Mothers and fathers of term infants (>= 37 weeks of gestational age, n=71), moderately preterm infants (>= 32-37 weeks of gestational age, n = 62) and very preterm infants (
Land management implications for ecosystem services in a South African rangeland
Petz, K. ; Glenday, J. ; Alkemade, J.R.M. - \ 2014
Ecological Indicators 45 (2014). - ISSN 1470-160X - p. 692 - 703.
semiarid succulent thicket - eastern cape - biodiversity loss - scale - 21st-century - conservation - metaanalysis - restoration - vegetation - resources
In South Africa, restoration and sustainable management of historically overgrazed and degraded rangelands are promoted to increase biodiversity and ecosystem service provision. This study evaluates different land management scenarios in terms of ecosystem services in a South African rangeland, the Baviaanskloof catchment. As measured data were limited, we used simple models to quantify and map the effect of the different combination of agricultural, nature conservation and restoration practices on multiple ecosystem services. The land management scenarios were evaluated against management targets set for individual ecosystem services. Results highlight how the provision of ecosystem services is related to land management as unmanaged, pristine ecosystems provide a different mix of ecosystem services than ecosystems recently restored or managed as grazing lands. Results also indicate that historically overgrazed lands provide no forage, may retain 40% less sediment and have 38% lower biodiversity, while providing 60% more fuel wood and supplying two and half times more water (i.e. retaining less water), than pristine or restored lands. We conclude that a combination of light grazing, low input agriculture, nature conservation and restoration is the best for the sufficient provision of multiple ecosystem services. Applying such mixed management would improve biodiversity, ecotourism and maintain forage production and regulating services on farmers' land. This management option also fits into and further optimizes local decision-makers' vision regarding the future management of the area. (C) 2014 Elsevier Ltd. All rights reserved.
Medication-Related Fall Incidents in an Older, Ambulant Population: The B-PROOF Study
Ham, A.C. ; Swart, K.M.A. ; Enneman, A.W. ; Dijk, S.C. van; Araghi, S.O. ; Wijngaarden, J.P. van; Zwaluw, N.L. van der; Brouwer, E.M. ; Dhonukshe-Rutten, R.A.M. ; Schoor, N.M. van; Cammen, T.J.M. van der; Lips, P. ; Uitterlinden, A.G. ; Witkamp, R.F. ; Stricker, B.H. ; Velde, N. van der; Groot, C.P.G.M. de - \ 2014
Drugs & Aging 31 (2014)12. - ISSN 1170-229X - p. 917 - 927.
randomized controlled-trial - risk-increasing drugs - primary-care database - physical performance - ophthalmic timolol - psychotropic-drugs - case-series - people - metaanalysis - community
Background Medication use is a potentially modifiable risk factor for falling; psychotropic and cardiovascular drugs have been indicated as main drug groups that increase fall risk. However, evidence is mainly based on studies that recorded falls retrospectively and/or did not determine medication use at the time of the fall. Therefore, we investigated the associations indicated in the literature between medication use and falls, using prospectively recorded falls and medication use determined at the time of the fall. Methods Data from the B-PROOF (B-vitamins for the prevention of osteoporotic fractures) study were used, concerning community-dwelling elderly aged >= 65 years. We included 2,407 participants with pharmacy dispensing records. During the 2- to 3-year follow-up, participants recorded falls using a fall calendar. Cox proportional hazard models were applied, adjusting for potential confounders including age, sex, health status variables and concomitant medication use. Results During follow-up, 1,147 participants experienced at least one fall. Users of anti-arrhythmic medication had an increased fall risk (hazard ratio [HR] 1.61; 95 % confidence interval [CI] 1.12-2.32) compared with non-users. Similarly, non-selective beta-blocker use was associated with an increased fall risk (HR 1.41 [95 % CI 1.12-1.78]), while statin use was associated with a lower risk (HR 0.81 [95 % CI 0.71-0.94]). Benzodiazepine use (HR 1.32 [95 % CI 1.02-1.71]), and antidepressant use (HR 1.40 [95 % CI 1.07-1.82]) were associated with an increased fall risk. Use of other cardiovascular and psychotropic medication was not associated with fall risk. Conclusion Our results strengthen the evidence for an increased fall risk in community-dwelling elderly during the use of anti-arrhythmics, non-selective beta-blockers, benzodiazepines, and antidepressant medication. Clinicians should prescribe these drugs cautiously and if possible choose safer alternatives for older patients.
Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study
Boers, I. ; Muskiet, F.A.J. ; Berkelaar, E. ; Schut, E. ; Penders, R. ; Hoenderdos, K. ; Jong, M.C. de; Wichers, H.J. - \ 2014
Lipids in Health and Disease 13 (2014). - ISSN 1476-511X - 13 p.
obese postmenopausal women - mediterranean-like diet - ischemic-heart-disease - hunter-gatherer - cardiovascular-disease - life-style - macronutrient - 21st-century - metaanalysis - individuals
Background The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a Paleolithic-type diet and may provide new insights in the pathophysiological mechanisms underlying the metabolic syndrome. In addition, more information on feasibility and designing an innovative dietary research program on the basis of a Palaeolithic-type diet was obtained. Methods Thirty-four subjects, with at least two characteristics of the metabolic syndrome, were randomized to a two weeks Palaeolithic-type diet (n¿=¿18) or an isoenergetic healthy reference diet, based on the guidelines of the Dutch Health Council (n¿=¿14). Thirty-two subjects completed the study. Measures were taken to keep bodyweight stable. As primary outcomes oral glucose tolerance and characteristics of the metabolic syndrome (abdominal circumference, blood pressure, glucose, lipids) were measured. Secondary outcomes were intestinal permeability, inflammation and salivary cortisol. Data were collected at baseline and after the intervention. Results Subjects were 53.5 (SD9.7) year old men (n¿=¿9) and women (n¿=¿25) with mean BMI of 31.8 (SD5.7) kg/m2. The Palaeolithic-type diet resulted in lower systolic blood pressure (-9.1 mmHg; P¿=¿0.015), diastolic blood pressure (-5.2 mmHg; P¿=¿0.038), total cholesterol (-0.52 mmol/l; P¿=¿0.037), triglycerides (-0.89 mmol/l; P¿=¿0.001) and higher HDL-cholesterol (+0.15 mmol/l; P¿=¿0.013), compared to reference. The number of characteristics of the metabolic syndrome decreased with 1.07 (P¿=¿0.010) upon the Palaeolithic-type diet, compared to reference. Despite efforts to keep bodyweight stable, it decreased in the Palaeolithic group compared to reference (-1.32 kg; P¿=¿0.012). However, favourable effects remained after post-hoc adjustments for this unintended weight loss. No changes were observed for intestinal permeability, inflammation and salivary cortisol. Conclusions We conclude that consuming a Palaeolithic-type diet for two weeks improved several cardiovascular risk factors compared to a healthy reference diet in subjects with the metabolic syndrome.
Kennis delen onder leraren: Een onderzoek naar de relaties tussen Occupational Self-Efficacy, Werk bevlogenheid, Human Resource Management en Kennis delen
Vermeulen, M. ; Runhaar, P.R. ; Konermann, J. ; Sanders, K. - \ 2014
Pedagogische Studiën 91 (2014)6. - ISSN 0165-0645 - p. 397 - 410.
job resources - performance - behavior - organizations - commitment - metaanalysis - motivation - workplace - community - exchange
Knowledge sharing is one of the professionalizetion processes and is an important factor in the competition between organizations and for innovation processes to sustain. In this study the central theme is the way knowledge sharing is affected by occupational self-efficacy (OSE), work engagement and High Commitment HRM (HC-HRM). In investigating these relations the AMO framework is used. The research data were obtained by 126 teachers from one secondary school. However from the regression analyses it was learned that the relationship between the variables OSE, HC HRM and work engagement with knowledge sharing was more complex than expected. Additional analyses by means of a three-way interaction analysis suggests that the combination of high experienced HC-HRM and low experienced OSE or the other way around is, related to more knowledge sharing. The findings are important for managers who want to promote processes of knowledge sharing in their school organization.
Letter to the Editor: Association of dietary, circulating, and supplement Fatty acids with coronary risk
Geleijnse, J.M. ; Brouwer, I.D. ; Kromhout, D. - \ 2014
Annals of Internal Medicine 161 (2014)6. - ISSN 0003-4819 - p. 457 - 458.
heart-disease - metaanalysis - prevention
Gains to species diversity in organically farmed fields are not propagated at the farm level
Schneider, M.K. ; Lüscher, G. ; Jeanneret, P. ; Jongman, R.H.G. - \ 2014
Nature Communications 5 (2014). - ISSN 2041-1723 - 9 p.
agri-environment schemes - different spatial scales - biodiversity conservation - conventional agriculture - european habitats - food-production - land-use - management - landscape - metaanalysis
Organic farming is promoted to reduce environmental impacts of agriculture, but surprisingly little is known about its effects at the farm level, the primary unit of decision making. Here we report the effects of organic farming on species diversity at the field, farm and regional levels by sampling plants, earthworms, spiders and bees in 1470 fields of 205 randomly selected organic and nonorganic farms in twelve European and African regions. Species richness is, on average, 10.5% higher in organic than nonorganic production fields, with highest gains in intensive arable fields (around þ45%). Gains to species richness are partly caused by higher organism abundance and are common in plants and bees but intermittent in earthworms and spiders. Average gains are insignificant þ4.6% at the farm and þ3.1% at the regional level, even in intensive arable regions. Additional, targeted measures are therefore needed to fulfil the commitment of organic farming to benefit farmland biodiversity.
Stimulating Informal Learning Activities Through Perceptions of Performance Appraisal Quality and Human Resource Management System Strength: A Two-Wave Study
Bednall, T. ; Sanders, K. ; Runhaar, P.R. - \ 2014
Academy of Management Learning & Education 13 (2014)1. - ISSN 1537-260X - p. 45 - 61.
firm performance - professional-development - employee perceptions - work practices - hr practices - feedback - organizations - teachers - model - metaanalysis
Employees' participation in informal learning activities benefits their workplace performance, and ultimately their long-term career development. While research has identified several individual- and organizational-level factors that promote participation, to date, the role of human resource management (HRM) in facilitating informal learning activities is not well understood. We investigate the effects of perceptions of performance appraisal quality and HRM system strength on three informal learning activities: reflection on daily activities, knowledge sharing with colleagues, and innovative behavior. Using a sample of 238 employees from 54 work teams, we examine over a year changes in levels of participation in the informal learning activities. Performance appraisal quality was found to be positively associated with increased participation in each activity over time, and HRM system strength positively moderated these relationships. Implications of the findings for educational institutions and other organizations are discussed.
Applying Intervention Mapping to develop a community-based intervention aimed at improved psychological and social well-being of unmarried teenage mothers in Uganda
Leerlooijer, J.N. ; Kok, G. ; Weyusya, J. ; Bos, A.E.R. ; Ruiter, R.A.C. ; Rijsdijk, E. ; Nshakira, N. ; Bartholomew, L.K. - \ 2014
Health Education Research 29 (2014)4. - ISSN 0268-1153 - p. 598 - 610.
hiv-1 infection - parenting teens - rural uganda - pregnancy - stigma - metaanalysis - adolescents - prevention - behavior - program
Out-of-wedlock pregnancy among adolescents in sub-Saharan Africa is a major concern, because of its association with health, social, psychological, economic and demographic factors. This article describes the development of the Teenage Mothers Project, a community-based intervention to improve psychological and social well-being of unmarried teenage mothers in rural Uganda. We used Intervention Mapping (IM) for systematically developing a theory and evidence-based comprehensive health promotion programme. A planning group consisting of community leaders, teenage mothers, staff of a community-based organization and a health promotion professional was involved in the six steps of IM: needs assessment, programme objectives, methods and applications, intervention design, planning for adoption and implementation and planning for evaluation. The programme includes five intervention components: community awareness raising, teenage mother support groups, formal education and income generation, counselling, and advocacy. The intervention components are based on a variety of theoretical methods, including entertainment education, persuasive communication, mobilization of social networks and social action. In conclusion, IM facilitated the planning group to structure the iterative, bottom-up, participatory design of the project in a real-life setting and to use evidence and theory. The article provides suggestions for the planning of support interventions for unmarried teenage mothers.
Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis
Hes, F.J. ; Ruano, D. ; Nieuwenhuis, M. ; Tops, C.M.J. ; Schrumpf, M. ; Nielsen, M. ; Huijts, P.E. ; Wijnen, J. ; Wagner, A. ; Gomet Garcia, E.B. ; Sijmons, R.H. ; Menko, F.H. ; Letteboer, T.G. ; Hoogerbrugge, N. ; Harryvan, J.L. ; Kampman, E. ; Morreau, H. ; Vasen, H.F. ; Wezel, T.G. van - \ 2014
Journal of Medical Genetics 51 (2014)1. - ISSN 0022-2593 - p. 55 - 60.
genome-wide association - susceptibility loci - genetic-variants - apc - mutations - hereditary - families - metaanalysis - mechanisms - phenotype
Background Colorectal adenomatous polyposis is associated with a high risk of colorectal cancer (CRC) and is frequently caused by germline mutations in APC or MUTYH. However, in about 20–30% of patients no underlying gene defect can be identified. In this study, we tested if recently identified CRC risk variants play a role in patients with >10 adenomas. Methods We analysed a total of 16 SNPs with a reported association with CRC in a cohort of 252 genetically unexplained index patients with >10 colorectal adenomas and 745 controls. In addition, we collected detailed clinical information from index patients and their first-degree relatives (FDRs). Results We found a statistically significant association with two of the variants tested: rs3802842 (at chromosome 11q23, OR=1.60, 95% CI 1.3 to 2.0) and rs4779584 (at chromosome 15q13, OR=1.50, 95% CI 1.2 to 1.9). The majority of index patients (84%) had between 10 and 100 adenomas and 15% had >100 adenomas. Only two index patients (1%), both with >100 adenomas, had FDRs with polyposis. Forty-one per cent of the index patients had one or more FDRs with CRC. Conclusions These SNPs are the first common, low-penetrant variants reported to be associated with adenomatous polyposis not caused by a defect in the APC, MUTYH, POLD1 and POLE genes. Even though familial occurrence of polyposis was very rare, CRC was over-represented in FDRs of polyposis patients and, if confirmed, these relatives will therefore benefit from surveillance.
Active and passive cigarette smoking and breast cancer risk: results from the EPIC cohort
Dossus, L. ; Boutron-Ruault, M.C. ; Kaaks, R. ; Gram, I.T. ; Vilier, A. ; Fervers, B. ; Manjer, J. ; Tjonneland, A. ; Olsen, A. ; Overvad, K. ; Chang-Claude, J. ; Boeing, H. ; Steffen, A. ; Trichopoulou, A. ; Lagiou, P. ; Sarantopoulou, M. ; Palli, D. ; Berrino, F. ; Tumino, R. ; Vineis, P. ; Mattiello, A. ; Bueno-de-Mesquita, H.B. ; Duijnhoven, F.J.B. van - \ 2014
International Journal of Cancer 134 (2014)8. - ISSN 0020-7136 - p. 1871 - 1888.
environmental tobacco-smoke - postmenopausal women - california teachers - 1st childbirth - never smokers - exposure - metaanalysis - association - carcinogens - reanalysis
Recent cohort studies suggest that increased breast cancer risks were associated with longer smoking duration, higher pack-years and a dose-response relationship with increasing pack-years of smoking between menarche and first full-term pregnancy (FFTP). Studies with comprehensive quantitative life-time measures of passive smoking suggest an association between passive smoking dose and breast cancer risk. We conducted a study within the European Prospective Investigation into Cancer and Nutrition to examine the association between passive and active smoking and risk of invasive breast cancer and possible effect modification by known breast cancer risk factors. Among the 322,988 women eligible for the study, 9,822 developed breast cancer (183,608 women with passive smoking information including 6,264 cases). When compared to women who never smoked and were not being exposed to passive smoking at home or work at the time of study registration, current, former and currently exposed passive smokers were at increased risk of breast cancer (hazard ratios (HR) [95% confidence interval (CI)] 1.16 [1.05–1.28], 1.14 [1.04–1.25] and 1.10 [1.01–1.20], respectively). Analyses exploring associations in different periods of life showed the most important increase in risk with pack-years from menarche to FFTP (1.73 [1.29–2.32] for every increase of 20 pack-years) while pack-years smoked after menopause were associated with a significant decrease in breast cancer risk (HR = 0.53, 95% CI: 0.34–0.82 for every increase of 20 pack-years). Our results provide an important replication, in the largest cohort to date, that smoking (passively or actively) increases breast cancer risk and that smoking between menarche and FFTP is particularly deleterious.
From research to action: enhancing crop yield through wild pollinators
Garibaldi, A. ; Carvalheiro, L.G. ; Leonhardt, S.D. ; Aizen, M.A. ; Blaauw, B.R. ; Isaacs, R. ; Kuhlman, M. ; Kleijn, D. ; Klein, A.M. ; Kremen, C. ; Morandin, L. ; Scheper, J.A. ; Winfree, R. - \ 2014
Frontiers in Ecology and the Environment 12 (2014)8. - ISSN 1540-9295 - p. 439 - 447.
bee abundance - ecosystem services - agricultural landscapes - diversity - communities - populations - resources - responses - metaanalysis - management
Recent evidence highlights the value of wild-insect species richness and abundance for crop pollination worldwide. Yet, deliberate physical importation of single species (eg European honey bees) into crop fields for pollination remains the mainstream management approach, and implementation of practices to enhance crop yield (production per area) through wild insects is only just beginning. With few exceptions, studies measuring the impacts of pollinator-supporting practices on wild-insect richness and pollination service success – particularly in relation to long-term crop yield and economic profit – are rare. Here, we provide a general framework and examples of approaches for enhancing pollinator richness and abundance, quantity and quality of pollen on stigmas, crop yield, and farmers' profit, including some benefits detected only through long-term monitoring. We argue for integrating the promotion of wild-insect species richness with single-species management to benefit farmers and society.
Identifying the ‘if’ for ‘if-then’ plans: Combining implementation intentions with cue-monitoring targeting unhealthy snacking behaviour
Verhoeven, A.A.C. ; Adriaanse, M.A. ; Vet, E. de; Fennis, B.M. ; Ridder, D.T.D. de - \ 2014
Psychology and Health 29 (2014)12. - ISSN 0887-0446 - p. 1476 - 1492.
habit strength - interventions - metaanalysis - breaking - enhance - weight - trial - power
Implementation intentions aimed at changing unwanted habits require the identification of personally relevant cues triggering the habitual response in order to be effective. To facilitate successful implementation intention formation, in the present study, planning was combined with cue-monitoring, a novel way to gain insight into triggers for unhealthy snacking. It was tested whether keeping a cue-monitoring diary and tailoring implementation intentions accordingly improves plan effectiveness. A 2 Monitoring (cue-monitoring, control)¿×¿2 Planning (implementation intention, goal intention) between subjects design was adopted. Participants (N = 161) monitored their unhealthy snacking behaviour for a week using either a cue-monitoring or a control diary. Participants then formulated a goal intention or an implementation intention tailored to their personal cue. Snacking frequency and caloric intake from unhealthy snacks were examined using a seven-day snack diary. The results did not indicate an interaction but yielded a main effect of Monitoring. Cue-monitoring either or not combined with implementation intentions reduced unhealthy snacking behaviour compared with control. Findings emphasise the effectiveness of cue-monitoring, suggesting that on the short term, cue-monitoring suffices to decrease unhealthy snacking, without additional benefit from planning. Future research should examine whether supplementing cue-monitoring with implementation intentions is required to establish long-term behaviour change maintenance.
Results of 2-year vitamin B treatment on cognitive performance
Zwaluw, N.L. van der; Dhonukshe-Rutten, R.A.M. ; Wijngaarden, J.P. van; Brouwer, E.M. ; Rest, O. van de; Veld, P.H. in 't; Enneman, A.W. ; Dijk, S.C. van; Ham, A.C. ; Swart, K.M.A. ; Velde, N. van der; Schoor, N.M. van; Cammen, T.J.M. van der; Uitterlinden, A.G. ; Lips, P. ; Kessels, R.P.C. ; Groot, C.P.G.M. de - \ 2014
Neurology 83 (2014)23. - ISSN 0028-3878 - p. 2158 - 2166.
folic-acid supplementation - randomized controlled-trial - placebo-controlled trial - alzheimers-disease - elderly-patients - double-blind - homocysteine - metaanalysis - impairment - folate
Objective: We investigated the effects of 2-year folic acid and vitamin B12 supplementation on cognitive performance in elderly people with elevated homocysteine (Hcy) levels. Methods: This multicenter, double-blind, randomized, placebo-controlled trial included 2,919 elderly participants (65 years and older) with Hcy levels between 12 and 50 µmol/L. Participants received daily either a tablet with 400 µg folic acid and 500 µg vitamin B12 (B-vitamin group) or a placebo tablet. Both tablets contained 15 µg vitamin D3. Data were available for global cognitive functioning assessed by Mini-Mental State Examination (n = 2,556), episodic memory (n = 2,467), attention and working memory (n = 759), information processing speed (n = 731), and executive function (n = 721). Results: Mean age was 74.1 (SD 6.5) years. Hcy concentrations decreased 5.0 (95% confidence interval -5.3 to -4.7) µmol/L in the B-vitamin group and 1.3 (-1.6 to -0.9) µmol/L in the placebo group. Cognitive domain scores did not differ over time between the 2 groups, as determined by analysis of covariance. Mini-Mental State Examination score decreased with 0.1 (-0.2 to 0.0) in the B-vitamin group and 0.3 (-0.4 to -0.2) in the placebo group (p = 0.05), as determined by an independent t test. Conclusions: Two-year folic acid and vitamin B12 supplementation did not beneficially affect performance on 4 cognitive domains in elderly people with elevated Hcy levels. It may slightly slow the rate of decline of global cognition, but the reported small difference may be attributable to chance. Classification of evidence: This study provides Class I evidence that 2-year supplementation with folic acid and vitamin B12 in hyperhomocysteinemic elderly people does not affect cognitive performance.
Wetlands Retention and Optimal Management of Waterfowl Habitat under Climate Change
Withey, P. ; Kooten, G.C. van - \ 2014
Journal of Agricultural and Resource Economics 39 (2014)1. - ISSN 1068-5502 - p. 1 - 18.
northern prairie wetlands - us - metaanalysis - temperature - impacts - canada - yields
We develop a positive mathematical programming model to investigate the impact of climate change on land use in the prairie pothole region of western Canada, with particular focus on wetlands retention. We examine the effect of climate change and biofuel policies that are implemented to mitigate climate change on wetlands retention. Simulation results indicate that a drier climate could decrease wetlands by as much as 38% if the externality benefits of wetlands are considered, but by nearly 80% if they are not. Reductions in wetlands are most pronounced in the south-central areas of the region.
Effect of moderate alcohol consumption on fetuin-A levels in men and women: post-hoc analyses of three open-label randomized crossover trials
Joosten, M.M. ; Schrieks, I.C. ; Hendriks, H.F.J. - \ 2014
Diabetes & Metabolic Syndrome: Clinical Research & Reviews 6 (2014). - ISSN 1871-4021 - 5 p.
community-dwelling adults - insulin-resistance - cardiovascular-disease - rancho bernardo - older-adults - risk - association - metaanalysis - expression - biomarkers
Background Fetuin-A, a liver-derived glycoprotein that impairs insulin-signalling, has emerged as a biomarker for diabetes risk. Although moderate alcohol consumption has been inversely associated with fetuin-A, data from clinical trials are lacking. Thus, we evaluated whether moderate alcohol consumption decreases circulating levels of fetuin-A. Methods We analyzed data of three separate open-label, randomized, crossover trials: 1) 36 postmenopausal women consuming 250 ml white wine (25 g alcohol) or white grape juice daily for 6 weeks, 2) 24 premenopausal women consuming 660 ml beer (26 g alcohol) or alcohol-free beer daily for 3 weeks, and 3) 24 young men consuming 100 ml vodka (30 g alcohol) orange juice or only orange juice daily for 4 weeks. After each treatment period fasting blood samples were collected. Results Circulating fetuin-A concentrations decreased in men after vodka consumption (Mean¿±¿SEM: 441¿±¿11 to 426¿±¿11 µg/ml, p¿=¿0.02), but not in women after wine (448¿±¿17 to 437¿±¿17 µg/ml, p¿=¿0.16) or beer consumption (498¿±¿15 to 492¿±¿15 µg/ml, p¿=¿0.48) compared to levels after each corresponding alcohol-free treatment. Post-hoc power analyses indicated that the statistical power to detect a similar effect as observed in men was 30% among the postmenopausal women and 31% among the premenopausal women. Conclusions In these randomized crossover trials, moderate alcohol consumption decreased fetuin-A in men but not in women. This sex-specific effect may be explained by the relatively short intervention periods or the low statistical power in the trials among women.
Association of dietary pattern and body weight with blood pressure in Jiangsu Province, China
Qin, Y. ; Boonstra, A. ; Pan, X. ; Zhao, J. ; Yuan, B. ; Dai, Yue ; Zhou, M. ; Geleijnse, J.M. ; Kok, F.J. ; Shi, Z. - \ 2014
BMC Public Health 14 (2014). - ISSN 1471-2458 - 16 p.
randomized controlled-trials - public-health - global burden - risk-factors - meat intake - mass index - hypertension - sodium - adults - metaanalysis
Background To identify risk factors, associations between dietary patterns, body mass index (BMI), and hypertension in a Chinese population. Methods Dietary intake was assessed in 2518 adults by a 3-day 24 h recall and a food frequency questionnaire. Salt and oil intake was assessed by weighing records. Four dietary patterns were identified using principal component analysis. Overweight and obesity was determined according to the Chinese cut-offs for BMI. High blood pressure was defined as systolic blood pressure¿=¿140 mmHg and/or diastolic blood pressure¿=¿90 mmHg. Prevalence ratios (PR) were calculated using Poisson regression. Results Of the subjects, 26.7% had high blood pressure. Subjects with overweight and obesity were more likely to have high blood pressure than those with normal weight (PR, 95% CI: 1.60, 1.40-1.87; 2.45, 2.11-2.85, respectively). Subjects with a ‘traditional’ dietary pattern were more likely to have high blood pressure (P for trend¿=¿0.001), whereas those with a ‘macho’ or ‘sweet tooth’ dietary pattern were less likely to have high blood pressure (P for trend¿=¿0.004 and ¿9 g/d, and blood pressure increased with salt intake (P for trend
Potential effect of salt reduction in processed foods on health
Hendriksen, M.A.H. ; Hoogenveen, R.T. ; Hoekstra, J. ; Geleijnse, J.M. ; Boshuizen, H.C. ; Raaij, J.M.A. van - \ 2014
American Journal of Clinical Nutrition 99 (2014)3. - ISSN 0002-9165 - p. 446 - 453.
cardiovascular-disease - blood-pressure - sodium restriction - cost-effectiveness - dietary-sodium - iodine intake - hypertension - metaanalysis - mortality - interventions
Background: Excessive salt intake has been associated with hypertension and increased cardiovascular disease morbidity and mortality. Reducing salt intake is considered an important public health strategy in the Netherlands. Objective: The objective was to evaluate the health benefits of salt-reduction strategies related to processed foods for the Dutch population. Design: Three salt-reduction scenarios were developed: 1) substitution of high-salt foods with low-salt foods, 2) a reduction in the sodium content of processed foods, and 3) adherence to the recommended maximum salt intake of 6 g/d. Health outcomes were obtained in 2 steps: after salt intake was modeled into blood pressure levels, the Chronic Disease Model was used to translate modeled blood pressures into incidences of cardiovascular diseases, disability-adjusted life years (DALYs), and life expectancies. Health outcomes of the scenarios were compared with health outcomes obtained with current salt intake. Results: In total, 4.8% of acute myocardial infarction cases, 1.7% of congestive heart failure cases, and 5.8% of stroke cases might be prevented if salt intake meets the recommended maximum intake. The burden of disease might be reduced by 56,400 DALYs, and life expectancy might increase by 0.15 y for a 40-y-old individual. Substitution of foods with comparable low-salt alternatives would lead to slightly higher salt intake reductions and thus to more health gain. The estimates for sodium reduction in processed foods would be slightly lower. Conclusion: Substantial health benefits might be achieved when added salt is removed from processed foods and when consumers choose more low-salt food alternatives.
Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial
Wijngaarden, J.P. van; Swart, K.M.A. ; Enneman, A.W. ; Dhonukshe-Rutten, R.A.M. ; Dijk, S.C. van; Ham, A.C. ; Brouwer, E.M. ; Zwaluw, N.L. van der; Sohl, E. ; Meurs, J.B.J. van; Zillikens, M.C. ; Schoor, N.M. van; Velde, N. van der; Brug, J. ; Uitterlinden, A.G. ; Lips, P. ; Groot, C.P.G.M. de - \ 2014
American Journal of Clinical Nutrition 100 (2014)6. - ISSN 0002-9165 - p. 1578 - 1586.
hip fracture - osteoporotic fractures - bone turnover - d deficiency - risk - metaanalysis - folate - level - women
Background: Elevated plasma homocysteine concentrations are a risk factor for osteoporotic fractures. Lowering homocysteine with combined vitamin B-12 and folic acid supplementation may reduce fracture risk. Objective: This study [B-vitamins for the PRevention Of Osteoporotic Fractures (B-PROOF)] aimed to determine whether vitamin B-12 and folic acid supplementation reduces osteoporotic fracture incidence in hyperhomocysteinemic elderly individuals. Design: This was a double-blind, randomized, placebo-controlled trial in 2919 participants aged =65 y with elevated homocysteine concentrations (12–50 µmol/L). Participants were assigned to receive daily 500 µg vitamin B-12 plus 400 µg folic acid or placebo supplementation for 2 y. Both intervention and placebo tablets also contained 600 IU vitamin D3. The primary endpoint was time to first osteoporotic fracture. Exploratory prespecified subgroup analyses were performed in men and women and in individuals younger than and older than age 80 y. Data were analyzed according to intention-to-treat and per-protocol principles. Results: Osteoporotic fractures occurred in 61 persons (4.2%) in the intervention group and 75 persons (5.1%) in the placebo group. Osteoporotic fracture risk was not significantly different between groups in the intention-to-treat analyses (HR: 0.84; 95% CI: 0.58, 1.21) or per-protocol analyses (HR: 0.81; 95% CI: 0.54, 1.21). For persons >80 y, in per-protocol analyses, osteoporotic fracture risk was lower in the intervention group than in the placebo group (HR: 0.27; 95% CI: 0.10, 0.74). The total number of adverse events (including mortality) did not differ between groups. However, 63 and 42 participants in the intervention and placebo groups, respectively, reported incident cancer (HR: 1.56; 95% CI: 1.04, 2.31). Conclusions: These data show that combined vitamin B-12 and folic acid supplementation had no effect on osteoporotic fracture incidence in this elderly population. Exploratory subgroup analyses suggest a beneficial effect on osteoporotic fracture prevention in compliant persons aged >80 y. However, treatment was also associated with increased incidence of cancer, although the study was not designed for assessing cancer outcomes. Therefore, vitamin B-12 plus folic acid supplementation cannot be recommended at present for fracture prevention in elderly people. The B-PROOF study was registered with the Netherlands Trial Register ( as NTR1333 and at as NCT00696414.
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