Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

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    We will mail you new results for this query: keywords==classical swine fever virus
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Reduced specificity of Erns antibody ELISAs for samples from piglets with maternally derived antibodies induced by vaccination of sows with classical swine fever marker vaccine CP7_E2alf
Meyer, D. ; Loeffen, W. ; Postel, A. ; Fritsche, S. ; Becher, P. - \ 2018
Transboundary and Emerging Diseases 65 (2018)2. - ISSN 1865-1674 - p. e505 - e508.
classical swine fever virus - CP7_E2alf - DIVA assay - E antibody ELISA - marker vaccine - maternally derived antibodies
Successful implementation of marker vaccines against classical swine fever virus is dependent on a reliable accompanying diagnostic assay that allows differentiation of infected from vaccinated animals (DIVA) as well as the development of a testing scheme during emergency vaccination. In this context, special attention needs to be paid to breeding farms, because the offspring of marker vaccinated sows possess maternally derived antibodies (MDAs). So far, limited information is available on the influence of MDAs on serological testing in the context of a DIVA strategy. Therefore, two commercially available Erns antibody ELISAs were compared, using serum samples of piglets with a high-to-moderate titre of MDAs against marker vaccine CP7_E2alf. False-positive results were detected by both Erns antibody ELISAs for serum samples of piglets with an age of up to 4 weeks. Interestingly, most samples tested false-positive in the first Erns antibody ELISA were identified correctly by the other Erns antibody ELISA and vice versa. In conclusion, in case of emergency vaccination of sows, the specificity of both ELISAs in newborn piglets younger than 4 weeks may be relatively low. This could be addressed in a testing strategy by either not sampling piglets up to the age of 4 weeks or using both ELISAs in a screening-confirmation set-up.
Economic aspects of antiviral agents to control Classical Swine Fever epidemics
Bergevoet, R.H.M. ; Asseldonk, M.A.P.M. van; Backer, J.A. - \ 2012
The Hague : LEI, part of Wageningen UR (Report / LEI : Research area Agriculture & entrepreneurship ) - ISBN 9789086156023
agrarische economie - antivirale middelen - classical swine fever virus - epidemieën - dierziekten - dierziektepreventie - economische aspecten - nederland - agricultural economics - antiviral agents - epidemics - animal diseases - animal disease prevention - economic aspects - netherlands
Outbreaks of contagious animal diseases such as Classical Swine Fever have detrimental effects on the livestock sector in an affected country as well as on society at large. The development of antiviral agents to control these epidemics can reduce the consequences of such outbreaks. The economic impact of applying these antiviral agents is until now unknown. In this report these consequences are investigated.
African swine fever: a threat to the Netherlands?
Loeffen, W.L.A. - \ 2008
Tijdschrift voor Diergeneeskunde 133 (2008)24. - ISSN 0040-7453 - p. 1066 - 1067.
varkenshouderij - afrikaanse varkenspest - varkensziekten - classical swine fever virus - pig farming - african swine fever - swine diseases
Een attenderingswaarschuwing om bij een verdachte situatie niet alleen rekening te houden met de klassieke varkenspest, maar ook met de Afrikaanse varkenspest
Persistentie van KVP-virus in gevaccineerde dieren: een risico? = Persistence of classical swine fever virus in vaccinated animals: a risk?
Loeffen, W.L.A. - \ 2008
Tijdschrift voor Diergeneeskunde 133 (2008)11. - ISSN 0040-7453 - p. 482 - 484.
landbouwbeleid - classical swine fever virus - varkenspest - varkenshouderij - ziektedistributie - verplichte vaccinatie - merkergenen - merkers - klassieke varkenspest - maatregelen - dierziektepreventie - agricultural policy - swine fever - pig farming - disease distribution - mandatory vaccination - marker genes - markers - classical swine fever - measures - animal disease prevention
Het is dit jaar geleden dat in Nederland het geval van klassieke varkenspest werd gedetecteerd. Het was het laatste geval in een epidemie die ruim een jaar had geduurd. Op dat moment waren we 429 besmette bedrijven verder, waren 12 miljoen varkens vernietigd en was de schade opgelopen tot meer dan 2 miljard euro. Om nog maar te zwijgen over de emotionele en psychotische schade bij vele betrokkenen. Sindsdien zit de angst voor een nieuwe uitbraak er goed in en zijn er veel maatregelen genomen om een herhaling te voorkomen. Een van die maatregelen is het aanpassen van het beleidsdraaiboek en het daarin opnemen van de optie om tijdens een volgende uitbraak eventueel te gaan vaccineren met een markergen. Het CV1 heeft veel onderzoek gedaan naar effectiviteit en veiligheid van een vaccinatiestrategie met markervaccins. Onder andere werd onderzocht wat de kans is dat gevaccineerde dieren na infectie een chronische infectie ontwikkelen en vervolgens langdurig infectieus zijn
Prevention and control of Foot-and-Mouth disease, classical swine fever and Avian influenza in the European Union: An integrated analysis of epidemiological, economic and social-ethical aspects
Asseldonk, M.A.P.M. van; Jong, M.C.M. de; Vlieger, J.J. de; Huirne, R.B.M. - \ 2005
Wageningen : Consortium for Veterinary Epidemiology and Economics - 141
mond- en klauwzeer - classical swine fever virus - aviaire influenzavirussen - ziektepreventie - ziektebestrijding - epidemiologie - europese unie - klassieke varkenspest - economische aspecten - sociale ethiek - foot and mouth disease - avian influenza viruses - disease prevention - disease control - epidemiology - european union - classical swine fever - economic aspects - social ethics
The recent outbreaks of Foot-and-Mouth Disease (FMD), Classical Swine Fever (CSF), and highly pathogenetic Avian Influenza (AI) in the European Union (EU) have shown that such contagious animal diseases can have a devastating impact in terms of animal welfare, economics and societal outcry and disturbance. Insights into the three interrelated, aspects of epidemiology, economics, and social-ethics are crucial in order to better prevent and control contagious diseases in the future. Because of the sometimes conflicting aspects a broad spectrum of stakeholders received a prominent position in the national public debate during and after the recent outbreaks. In order to quantify the impact of alternative views by alternative stakeholders science-based models are a prerequisite. The main goal of the project is therefore to conduct an integrated analysis of epidemiological, economic and social-ethical aspects of (potential) control strategies. First the results of a survey are presented which focused on prioritising epidemiological, economic and social-ethical aspects. Subsequently, an integrated analysis is described in order to obtain insight into the impact of the above mentioned differences between stakeholders. A detailed analysis is presented for six EU member states and three contagious diseases (FMD, CSFand AI).
Risk analysis of classical swine fever introduction
Vos, C.J. de - \ 2005
Wageningen University. Promotor(en): Ruud Huirne, co-promotor(en): Helmut Saatkamp. - Wageningen : Ponsen & Looijen BV - ISBN 9085042178 - 173
classical swine fever virus - varkenspest - risicoschatting - cost effective analysis - ziektepreventie - risicofactoren - nederland - europese unie - swine fever - risk assessment - cost effectiveness analysis - disease prevention - risk factors - netherlands - european union
Economic welfare analysis of simulated control strategies for Classical Swine Fever epidemics
Mangen, M.J.J. - \ 2002
Wageningen University. Promotor(en): A.A. Dijkhuizen; M. Nielen; A.M. Burrell. - S.l. : S.n. - ISBN 9789058086211 - 186
varkens - classical swine fever virus - varkenspest - ziekteoverdracht - ziektebestrijding - epidemiologie - vaccinatie - welvaartseconomie - kosten - verliezen - consumentengedrag - simulatiemodellen - economie - nederland - pigs - swine fever - disease transmission - disease control - epidemiology - vaccination - welfare economics - costs - losses - consumer behaviour - simulation models - economics - netherlands
<strong><font size="6"><p align="RIGHT"></p></strong><p align="RIGHT"> </p></font><p>Keywords: Classical swine fever; contagious disease; epidemiological model; sector-level market and trade model; simulation; economic welfare analysis; densely and sparsely populated areas; supplementary animal welfare measures; the Netherlands.</p><font size="2"><p> </p></font><p>A sector-level and trade market model and a generic, spatial, temporal and stochastic epidemiological model are used to simulate the epidemiological and economic effects of different measures to control classical swine fever (CSF) epidemics in different regions in the Netherlands. The control measures include the current EU legislation (stamping-out infected herds; tracing contact herds and installing quarantine zones), preventive slaughtering or an emergency vaccination strategy with delayed destruction and intra-community trade as additional control measures. In addition, the effects of supplementary animal welfare measures to interrupt piglet production during a CSF epidemic are analysed. Different trade scenarios are simulated: a partial trade ban for the quarantine zones only or a total export ban on all Dutch live pigs. Aggregating the welfare changes of the different stakeholders (pig producers, consumers and government) provides results on the net welfare effect for the Dutch economy.</p><p>Economic and epidemiological results suggest that measures to control CSF epidemics should be dependent on geographical circumstances. In a sparsely populated pig area, the measures defined by EU legislation are appropriate, whereas in a densely populated area additional control measures, e.g. emergency vaccination and/or preventive slaughter, are needed. The current political climate favours preventive slaughter for the Dutch situation. Furthermore, the option of supplementary animal welfare measures to interrupt piglet production during the epidemic is rejected on economic grounds. Results indicate that rendering capacities should be reserved for carcasses from infected and preventively slaughtered farms, and used to destroy pig carcasses slaughtered for animal welfare reasons only if capacity permits.
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