- E.J. Brink (8)
- P. Deurenberg (1)
- Janneke Dopheide (1)
- Th. Dopheide (1)
- J. Dopheide (9)
- Karianna F.M. Teunissen-Beekman (1)
- J.M. Geleijnse (8)
- Marianne Geleijnse (1)
- J.G.A.J. Hautvast (1)
- F.M. Hollander (1)
- H.J. Holterman (3)
- Elizabeth J. Brink (1)
- Stephan J.L. Bakker (1)
- P.C. Jansen (1)
- R. Kwant (1)
- P.W. Leeuw de (4)
- A.A. Pronk (1)
- L. Robroch (1)
- N.M. Roos de (1)
- C.G. Schalkwijk (1)
- J. Serroyen (2)
- H. Siepel (1)
- J. Smits (1)
- K.F.M. Teunissen-Beekman (6)
- Peter W. Leeuw de (1)
- J.A. Weststrate (1)
Effect of increased protein intake on renal acid load and renal hemodynamic responses
Teunissen-Beekman, Karianna F.M. ; Dopheide, Janneke ; Geleijnse, Marianne ; Bakker, Stephan J.L. ; Brink, Elizabeth J. ; Leeuw, Peter W. de; Baak, Marleen A. van - \ 2016
Physiological Reports 4 (2016)5. - ISSN 2051-817X - 10 p.
Acid load - Carbohydrate - Glomerular filtration rate - Kidney - Protein
Increased protein intake versus maltodextrin intake for 4 weeks lowers blood pressure. Concerns exist that high-protein diets reduce renal function. Effects of acute and 4-week protein intake versus maltodextrin intake on renal acid load, glomerular filtration rate and related parameters were compared in this study. Seventy-nine overweight individuals with untreated elevated blood pressure and normal kidney function were randomized to consume a mix of protein isolates (60 g/day) or maltodextrin (60 g/day) for 4 weeks in energy balance. Twenty-four-hour urinary potential renal acid load (uPRAL) was compared between groups. A subgroup (maltodextrin N = 27, protein mix N = 25) participated in extra test days investigating fasting levels and postprandial effects of meals supplemented with a moderate protein- or maltodextrin-load on glomerular filtration rate, effective renal plasma flow, plasma renin, aldosterone, pH, and bicarbonate. uPRAL was significantly higher in the protein group after 4 weeks (P ≤ 0.001). Postprandial filtration fraction decreased further after the protein-supplemented breakfast than after the maltodextrin-supplemented breakfast after 4 weeks of supplementation (P ≤ 0.001). Fasting and postprandial levels of glomerular filtration rate, effective renal plasma flow, renin, aldosterone, angiotensin-converting enzyme, pH and bicarbonate did not differ between groups. In conclusion, 4 weeks on an increased protein diet (25% of energy intake) increased renal acid load, but did not affect renal function. Postprandial changes, except for filtration fraction, also did not differ between groups. These data suggest that a moderate increase in protein intake by consumption of a protein mix for 4 weeks causes no (undesirable) effects on kidney function in overweight and obese individuals with normal kidney function.
Dietary proteins improve endothelial function under fasting conditions but not in the postprandial state, with no effects on markers of low-grade inflammation
Teunissen-Beekman, K.F.M. ; Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J. ; Brink, E.J. ; Leeuw, P.W. de; Schalkwijk, C.G. ; Baak, M.A. van - \ 2015
British Journal of Nutrition 114 (2015)11. - ISSN 0007-1145 - p. 1819 - 1828.
Endothelial dysfunction (ED) and low-grade inflammation (LGI) have a role in the development of CVD. The two studies reported here explored the effects of dietary proteins and carbohydrates on markers of ED and LGI in overweight/obese individuals with untreated elevated blood pressure. In the first study, fifty-two participants consumed a protein mix or maltodextrin (3×20 g/d) for 4 weeks. Fasting levels and 12 h postprandial responses of markers of ED (soluble intercellular adhesion molecule 1 (sICAM), soluble vascular cell adhesion molecule 1 (sVCAM), soluble endothelial selectin and von Willebrand factor) and markers of LGI (serum amyloid A, C-reactive protein and sICAM) were evaluated before and after intervention. Biomarkers were also combined into mean Z-scores of ED and LGI. The second study compared 4 h postprandial responses of ED and LGI markers in forty-eight participants after ingestion of 0·6 g/kg pea protein, milk protein and egg-white protein. In addition, postprandial responses after maltodextrin intake were compared with a protein mix and sucrose. The first study showed significantly lower fasting ED Z-scores and sICAM after 4 weeks on the high-protein diet (P=0·02). The postprandial studies found no clear differences of ED and LGI between test meals. However, postprandial sVCAM decreased more after the protein mix compared with maltodextrin in both studies (P=0·04). In conclusion, dietary protein is beneficial for fasting ED, but not for fasting LGI, after 4 weeks of supplementation. On the basis of Z-scores, postprandial ED and LGI were not differentially affected by protein sources or carbohydrates.
Differential effects of proteins and carbohydrates on postprandial blood pressure-related responses
Teunissen-Beekman, K.F.M. ; Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Leeuw, P.W. de; Serroyen, J. ; Baak, M.A. van - \ 2014
British Journal of Nutrition 112 (2014)4. - ISSN 0007-1145 - p. 600 - 608.
randomized controlled-trials - plasma amino-acids - healthy-subjects - insulin responses - dietary-protein - overweight adults - energy-intake - whey-protein - glucose - fructose
Diet composition may affect blood pressure (BP), but the mechanisms are unclear. The aim of the present study was to compare postprandial BP-related responses to the ingestion of pea protein, milk protein and egg-white protein. In addition, postprandial BP-related responses to the ingestion of maltodextrin were compared with those to the ingestion of sucrose and a protein mix. We hypothesised that lower postprandial total peripheral resistance (TPR) and BP levels would be accompanied by higher plasma concentrations of nitric oxide, insulin, glucagon-like peptide 1 (GLP-1) and glucagon. On separate occasions, six meals were tested in a randomised order in forty-eight overweight or obese adults with untreated elevated BP. Postprandial responses of TPR, BP and plasma concentrations of insulin, glucagon, GLP-1 and nitrite, nitroso compounds (RXNO) and S-nitrosothiols (NOx) were measured for 4 h. No differences were observed in TPR responses. Postprandial BP levels were higher after the ingestion of the egg-white-protein meal than after that of meals containing the other two proteins (P
|Differences in postprandial hemodynamic response on a high protein versus a high carbohydrate diet
Dopheide, J. ; Teunissen-Beekman, K.F.M. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Baak, M.A. van - \ 2013
Annals of Nutrition & Metabolism 62 (2013). - ISSN 0250-6807 - p. 152 - 152.
|Increased Dietary Protein Intake Lowers Blood Pressure in Overweight Subjects
Dopheide, J. ; Teunissen-Beekman, K.F.M. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Baak, M.A. van - \ 2013
Annals of Nutrition & Metabolism 62 (2013). - ISSN 0250-6807 - p. 148 - 148.
Blood pressure decreases more after high-carbohydrate meals than after high-protein meals in overweight adults with elevated blood pressure, but there is no difference after 4 weeks of consuming a carbohydrate-rich or protein-rich diet
Teunissen-Beekman, K.F.M. ; Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J. ; Brink, E.J. ; Leeuw, P.W. de; Serroyen, J. ; Baak, M.A. van - \ 2013
The Journal of Nutrition 143 (2013)4. - ISSN 0022-3166 - p. 424 - 429.
systemic hemodynamic-changes - randomized-trial - sympathetic activity - elderly subjects - humans - insulin - activation - ingestion - hormone - glucose
The replacement of dietary carbohydrates with proteins can lower blood pressure (BP), but the mechanisms remain unclear. This randomized, double-blind, parallel-group study aimed to compare 12-h postprandial sympathetic and hemodynamic responses after high-protein (HP) meals and high-carbohydrate (HC) meals. Fifty-two men and women with untreated elevated BP were tested on d 1 and after 4 wk of supplementation [3 × 20 g protein (HP) or maltodextrin (HC) per day]. No between-group differences were found in postprandial plasma norepinephrine on d 1 and at wk 4. On d 1, postprandial mean arterial pressure (MAP) decreased more in the HC group than in the HP group (P = 0.002). This difference was not present at 4 wk, because the postprandial decline in MAP tended to become larger in the HP group after 4 wk of supplementation (P = 0.07). On both test days, postprandial total peripheral resistance tended to decrease more in the HC group (P <0.08). After 4 wk of supplementation, cardiac output tended to increase more in the HC group (P = 0.08). In conclusion, ingestion of an HP diet induced a smaller decrease in BP on d 1 than did ingestion of an HC diet. This difference disappeared after 4 wk due to a more pronounced decrease in BP in the HP group after 4 wk than on d 1. These findings cannot explain the BP-lowering effect ascribed to dietary proteins.
Protein supplementation lowers blood pressure in overweight adults: effect of dietary proteins on blood pressure (PROPRES), a randomized trail
Teunissen-Beekman, K.F.M. ; Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Leeuw, P.W. de; Baak, M.A. van - \ 2012
American Journal of Clinical Nutrition 95 (2012)4. - ISSN 0002-9165 - p. 966 - 971.
carbohydrate intake - hypertension - excretion - markers - women - fat
Background: Dietary protein intake may help to manage blood pressure (BP) and prevent complications associated with elevated BP. Objective: The objective of this study was to determine whether 4 wk of increased protein intake (~25% compared with ~15% of energy intake that isoenergetically replaces carbohydrate intake) lowers office and daytime BP compared with increased carbohydrate intake. Design: A randomized, double-blind, parallel study compared consumption of 3 × 20 g protein/d (20% pea, 20% soy, 30% egg, and 30% milk-protein isolate) with 3 × 20 g maltodextrin/d. Protein or maltodextrin were isoenergetically substituted for a sugar-sweetened drink. Primary outcomes were office and daytime BP. A total of 99 men and women [age range: 20–70 y; BMI (in kg/m2): 25–35] with untreated elevated BP (BP =130/85 and
|Increased dietary protein intake lowers blood pressure in overweight subjects
Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Baak, M.A. van - \ 2011
Journal of Hypertension 29 (2011)Suppl.. - ISSN 0263-6352 - p. e267 - e267.
Objective: Several intervention trials have shown that diet composition affects blood pressure (BP). In this study we focused on the effect of dietary protein content on BP. Design and Method: In this randomized double-blind parallel group study, 94 adult untreated overweight subjects with mildly elevated BP (BMI 25-35 kg/m2, BP > 130/85 and <160/100 mm Hg) were included. After a 2-week run-in period on a weight-maintaining standardized diet (15 en% protein (P), 30 en% fat (F) and 55 en% carbohydrate (C)), subjects were randomized to a high P or a high C diet for 4 weeks. On the high C diet 60 g of C of the run-in diet was replaced by 3x20 g of maltodextrin supplements, on the high P diet 60 g of C was replaced by 3x20 g of a protein supplement (mixture of 20% pea, 20% soy, 30% egg and 30% milk protein isolate). Supplements were matched for Na, P, K, Ca and Mg content and taken with each meal. Office and 24-h ambulatory blood pressures (ABP) were assessed at the end of the run-in and after 4 weeks supplement use. BP differences between groups after 4 weeks were analyzed by ANCOVA with BP at the end of the run-in as covariate. Results :At the end of run-in office BP (mean ± SE) was 142.6 ± 1.6/92.2 ± 0.9 mm Hg in the C and 143.3 ± 1.8/92.9 ± 1.0 mm Hg in the P group; daytime ambulatory BPs were 147.5 ± 1.8/91.0 ± 1.1 mm Hg and 147.2 ± 1.8/92.5 ± 1.2 mm Hg respectively. After 4 weeks, office SBP and DBP were lower in the P than in the C group (-4.9 mm Hg (95% CI -1.5, -8.2), p = 0.005 and - 2.7 mm Hg (95% CI -0.1, -5.4), p = 0.045) and daytime ambulatory SBP tended to be (-4.1 mm Hg (95% CI + 0.2, -8.3), p = 0.06). No significant between-group differences in daytime ambulatory DBP (-1.7 mm Hg (95% CI + 1.3, -4.8), p = 0.26) or night-time BP were found. Conclusions: An increase in dietary protein content, in exchange for dietary carbohydrates (glucose), in a weight-maintaining diet lowers blood pressure in overweight subjects with mild blood pressure elevation.
Differences in postprandial hemodynamic response on a high protein versus a high carbohydrate diet
Dopheide, J. ; Geleijnse, J.M. ; Bakker, S.J.L. ; Brink, E.J. ; Baak, M.A. van - \ 2011
Journal of Hypertension 29 (2011)eSuppl.A. - ISSN 0263-6352 - p. e525 - e526.
Objective: Several intervention trials have shown that diet composition affects blood pressure (BP). In this study we focused on postprandial hemodynamic changes on a high carbohydrate versus a high protein diet. Design and Method: In this randomized double-blind parallel group study, 53 adult untreated overweight subjects with mildly elevated BP (BMI 25-35 kg/m2, BP > 130/85 and <160/100 mm Hg) were included. After a 2-week run-in period on a weight-maintaining standardized diet (15 en% protein (P), 30 en% fat (F) and 55 en% carbohydrate (C)), subjects were randomized to a high P or a high C diet for 4 weeks. On the high C diet 60 g of C of the run-in diet was replaced by 3x20 g of maltodextrin supplements, on the high P diet 60 g of C was replaced by 3x20 g of a protein supplement (mixture of 20% pea, 20% soy, 30% egg and 30% milk protein isolate). Supplements were matched for Na, P, K, Ca and Mg content and taken with each meal. Postprandial hemodynamic responses to the diets were determined on day 1 and day 28 of supplement use over 4 hours after meal ingestion. Differences in the postprandial responses between groups were analyzed by ANCOVA with baseline fasting values as covariate.
Study on drop size distributions of evaporating water and saline sprays
Holterman, H.J. ; Pronk, A.A. - \ 2011
In: Lasermethoden in der Strömungsmesstechnik. 19. Fachtagung, Ilmenau, Germany, 6 - 8 September, 2011. - Karlsruhe : Deutsche Gesellschaft für Laser-Anemometrie GALA - ISBN 9783980561372 - p. 34.1 - 34.8.
Self-reported use of vitamins and other nutritional supplements in adult patients with cystic fibrosis. Is daily practice in concordance with recommendations?
Hollander, F.M. ; Roos, N.M. de; Dopheide, J. - \ 2010
International Journal for Vitamin and Nutrition Research 80 (2010)6. - ISSN 0300-9831 - p. 408 - 415.
bone health - d insufficiency - children - deficiency
Background: In cystic fibrosis (CF), prophylactic supplementation of the fat-soluble vitamins A, D, E, and K is recommended. Limited data is available describing vitamin prescription adherence by adult patients. The aim of this study was to assess the use of prescribed vitamins and other nutritional supplements by adult CF patients. Methods: All adult CF patients (n = 111) registered at the Utrecht CF Center were invited to participate in a telephone survey on supplement use. Supplemental vitamin intakes were compared with recommendations. In a subsample, associations between supplemental intake and serum vitamin D and E values were assessed. Results: In this study 80 % of the patients reported the use of vitamin and/or mineral supplements. Fat-soluble vitamins were used by 43 % of pancreatic-sufficient (PS) and 81 % of pancreatic-insufficient (PI) patients. Of PI patients reporting supplemental vitamin use, only 9 % met the recommendations for vitamin A, 32 % for vitamin D, 59% for vitamin E, and 81 % for vitamin K. Multivitamin supplements were used by 42 % of PI and by 29 % of PS patients. Other nutritional supplements were rarely used. Conclusion: A high percentage of PI patients use fat-soluble vitamins below recommendations. Therefore adequate monitoring of vitamin supplementation and status is warranted
Heidebeheer en fauna : verslag veldwerkplaats Droog Zandlandschap Strabrechtse Heide, 4 juni 2009
Smits, J. ; Siepel, H. - \ 2009
[S.l. : S.n. - 5
zandgronden - heidegebieden - begrazing - natuurgebieden - herstelbeheer - noord-brabant - sandy soils - heathlands - grazing - natural areas - restoration management
De Strabrechtse Heide is een 1500 hectare groot heidegebied ten zuidoosten van Eindhoven. Het is een zeer gevarieerd gebied met onder andere hoogteverschillen, waterpartijen, zandverstuivingen, Calluna (dopheide) en akkercomplexen. Het gebied is grotendeels in eigendom van Staatsbosbeheer sinds 1954. De belangrijkste beheermaatregelen die Staatsbosbeheer neemt zijn grazen (koeien en schapen), plaggen (visgraat), maaien (Pijpenstro) en branden, daarnaast is er een actief beheer voor het behoud van het stuifzandgebied en ligt er zo’n 15 hectare akkerland waar biologische landbouw op bedreven wordt. Deze akkercomplexen worden tevens gebruikt om het plagsel op te verwerken. Van mei tot november maakt de Staatsbosbeheer ook gebruik van twee soorten runderen: Black Angus en Blonde d’Acquitaine. Deze runderen kunnen zich verder vrij door het gebied bewegen. De Black Angus graaft gaten, op zoek naar mineralen, waardoor er dynamiek ontstaat. Sinds 1967 wordt er gebruik gemaakt van schapen. Tegenwoordig bestaat de kudde uit zo’n 350 tot 400 dieren, plus 300 lammeren na de lammertijd. De schaapherder volgt met de kudde een door Staatsbosbeheer gemaakt begrazingsplan
Comparison of 1D PDA sampling methods to obtain drop size and velocity distributions inside a spray cone of agricultural nozzles
Holterman, H.J. - \ 2009
In: Lasermethoden in der Stromungsmesstechnik, Karlsruhe, Germany, 8 - 10 September, 2009. - Erlangen, Duitsland : Deutsche Gesellschaft für Laser-Anemometrie GALA - ISBN 9783980561358 - p. 35.1 - 35.8.
In agriculture, spray drift research is carried out in field experiments and by computer simulation. Regarding the latter approach, accurate knowledge of the initial spray is required. Not only is the overall drop size distribution of the spray an important factor in the spraying process, but also its local variation within the spray cone below a nozzle. Furthermore, the velocity distribution of drops in the spray cone has to be considered, which is a function of drop size and location in the spray cone. A PDA system is well-suited to carry out measurements on drop size and velocity. This study compares four scanning methods using a 1D PDA system to characterize the spray cone of a flat fan nozzle. These methods differ in operator time and handlings during the measurement and data processing afterwards. Fortunately, all methods give similar results so one is free to choose one’s preferred method. Although in some cases 2D or 3D PDA systems may be ideal, this study shows that a 1D system still offers possibilities for spray characterizations
Effects of PDA sampling techniques on spectral characteristics of Agricultural sprays
Holterman, H.J. - \ 2008
In: Lasermethoden in der Strömungsmesstechnik, Karlsruhe, Germany, 9 - 11 September, 2008. - Karlsruhe,Duitsland : Deutsche Gesellschaft für Laser-Anemometrie GALA - ISBN 9783980561341 - p. 36.1 - 36.8.
Verdamping van korte vegetaties in natte natuurgebieden
Jansen, P.C. - \ 1995
H2O : tijdschrift voor watervoorziening en afvalwaterbehandeling 28 (1995)15. - ISSN 0166-8439 - p. 467 - 471.
evapotranspiratie - heidegebieden - hydrologie - meting - monitoring - plantengemeenschappen - natuurgebieden - evapotranspiration - heathlands - hydrology - measurement - plant communities - natural areas
De verdamping is belangrijk voor het waterkwantiteitsbeheer van natte natuurgebieden. Het is echter nog onvoldoende bekend in welke mate vegetaties in dergelijke gebieden de transpiratie reduceren en in hoeverre dit gecompenseerd wordt door een toename van de evaporatie. Met lysimeters is voor drie korte vegetatietypen de potentiële verdamping en de verdamping onder erg natte omstandigheden bepaald. Het betreft vegetaties waarin dopheide, pijpestrootje en schraalgraslandsoorten domineren. Als referentie is de verdamping van gazongras gemeten. Deze is vergeleken met de referentie-verdamping berekend volgens de methode van Makkink. Vervolgens zijn voor de drie vegetatietypen gewasfactoren vastgesteld.
Does variation in palatability affect the postprandial response in energy expenditure?
Weststrate, J.A. ; Dopheide, Th. ; Robroch, L. ; Deurenberg, P. ; Hautvast, J.G.A.J. - \ 1990
Appetite 15 (1990). - ISSN 0195-6663 - p. 209 - 219.
Een wiskundig model voor de heide
Berendse, F. ; Kwant, R. - \ 1984
Tijdschrift / Vereniging Koninklijke Nederlandsche Heide Maatschappij november (1984). - ISSN 0165-0017 - p. 371 - 374.
heidegebieden - wiskunde - voedingsstoffen - plantengemeenschappen - plantenvoeding - statistiek - plaggen steken - heathlands - mathematics - nutrients - plant communities - plant nutrition - statistics - sod cutting
De effecten van plaggen en maaien op het concurrentievermogen van dopheide en pijpestrootje zijn via een wiskundig model nagegaan. Daarbij is allereerst bepaald wat het effect is van een verhoging van stikstof- en fosfaatbeschikbaarheid op de soortensamenstelling van de vegetatie