Avian Influenza: Prevention and Control

Proceedings of the Frontis workshop on Avian Influenza:
Prevention and Control
Wageningen, The Netherlands 13-15 October 2003
Editor:
R.S. Schrijver
Animal Sciences Group, Wageningen University and Research Centre,
Lelystad, The Netherlands
G. Koch
Central Institute for Disease Control, Wageningen University and
Research Centre, Lelystad, The Netherlands
Series editor:
R.J. Bogers
Frontis – Wageningen International Nucleus for Strategic
Expertise
Wageningen University and Research Centre, Wageningen, The
Netherlands
About the book | Table of Contents
Avian Influenza has become one of the biggest threats for human
and animal health. The old paradigm was that the disease in
waterfowl, poultry, pigs and man was caused by separate viruses
that each stayed reasonably well within their own niche. The only
danger to man was considered being infected by pigs, being the
mixing vessel, where avian and human influenza viruses could come
together and exchange genetic material to form new viruses that
are potentially dangerous to man.
This has dramatically proven wrong during the last decade, with
huge outbreaks in the USA, Europe, and Asia. The H5N1 strain that
caused human deaths in Hong Kong appeared to be transmitted
directly from poultry to man. This initiated sudden awareness
that pigs were not a necessary intermediate in the transmission
chain. During the AI outbreaks in Italy, mutation of
low-pathogenicity viruses into high-pathogenicity viruses in
poultry appeared another new threat, and further evidence that
the poultry sector had a wolf in sheep's clothing. It put
pressure on development of diagnostic methods that could be used
in large monitoring programmes.
In The Netherlands a human fatality, after increased reports of
conjunctivitis during a H7N7 outbreak, signalled that different
AI strains could be fatal to man. Also, the huge economic losses
and difficulties in controlling the spread of the infection in
densely populated poultry areas, problems with vaccination and
lack of marker vaccines demonstrated that the current control
policy must be improved. These events led to an international AI
conference with experts from Asia, USA and Europe.
In this book you will find new views on the issues, expert
opinions and the results of in-depth discussions among avian
experts of around the world that do not want to give up against
this dangerous virus.
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