2024-03-29T15:25:45+01:00
https://library.wur.nl/oai
oai:library.wur.nl:wurpubs/408891
2024-03-09
urn:nbn:nl:ui:32-408891
2024-03-09
urn:nbn:nl:ui:32-408891/mods
Comparison of different exposure assessment methods to estimate the long-term dietary exposure to dioxins and ochratoxin A
Boon
P.E.
aut
Bonthuis
M.
aut
van der Voet
H.
073559733
0000-0003-0802-7382
0000000396439087
aut
van Klaveren
J.D.
12463057X
aut
text
info:eu-repo/semantics/article
2011
10.1016/j.fct.2011.05.009
79960845971
000295188600012
en
Long-term exposures to dioxins (PCCD/F and dioxin-like PCBs) and ochratoxin A were calculated using food consumption data of the European concise database combined with concentration data of the Netherlands (NL) using a deterministic approach. To refine these assessments, exposures were also calculated using three long-term exposure models, observed individual means (OIM), Iowa State University Foods (ISUF), and betabinomial-normal (BBN) models, combined with individual food consumption data of NL. BBN and ISUF correct the variation in long-term exposure for the within-person variation, whereas OIM calculates the mean exposure over the days in the food consumption survey. Exposures obtained with the concise database were highest, and those obtained with OIM higher than with BBN and ISUF. Contribution of the major sources of exposure differed between the concise database and the three models. Given the constraints of the concise database, exposures obtained with this database should be interpreted as a first tier assessment. Preferably, refined assessments using models that correct the variation in long-term exposure for the within-person variation combined with individual food consumption data and national concentration data should be used to assess the long-term exposure. We recommend the use of BBN since it can model exposure distributions that depend on covariates
PE&RC
Biometris
episodically consumed foods
PE&RC
Biometris
Food and Chemical Toxicology
49
9
1979
1988
02786915
urn:nbn:nl:ui:32-408891/obj
2024-03-09
http://purl.org/eprint/accessRights/RestrictedAccess