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Developing integrated strategies to reduce the disease burden of mycotoxin contamination in Ethiopia
Awol, Sadik Jemal2026
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  • Smallholder farmers in Ethiopia have limited resources and inadequate knowledge of good agricultural and storage practices, resulting in frequent mycotoxin contamination of staple crops. Information on the health impacts of mycotoxins and the relationships between farming practices and contamination remains fragmented. Generating evidence on contamination levels, associated health burdens, and management practices is therefore essential to inform policies that protect public health and supp ...

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    Sugared proteins, unsweet outcomes : glycation, RAGE signaling, and their relation to diabetes and Alzheimer’s Disease
    Croes, Cresci-Anne C.C.2026
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  • Protein glycation is a non-enzymatic reaction between reducing sugars and amino groups in proteins, resulting in the formation of advanced glycation end-products (AGEs). These modifications accumulate during aging and are accelerated under hyperglycemic conditions such as type 2 diabetes. Although the chemistry of glycation and the Maillard reaction is well characterized, the biological consequences of distinct glycation chemistries remain incompletely understood. In particular, it is uncle ...

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    Pathways to perception : sexual differentiation and pheromone communication in parasitoid wasps
    Williams, Aidan Thomas2026
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  • Insects have evolved genetic pathways that determine whether they develop as a male or female. These pathways also shape physical and behavioural differences in their pheromone communication systems to facilitate how they share and process information. Research into how these pathways regulate these differences has primarily been limited to the fruit fly Drosophila melanogaster, which utilizes a so-called dedicated labelled-line system to perceive and process pheromones. Hymenoptera – ants, ...

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    Multifunctional and stakeholder-informed agricultural landscape redesign in the north China plain
    Cheng, Jiali2026
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  • Agricultural landscapes support the provisioning of ecosystem services (ESs), such as food production, pest control, and nutrient cycling, while agricultural land use also generates disservices, including biodiversity loss, nutrient runoff, and greenhouse gas emissions. In the simplified landscapes of the North China Plain (NCP), intensive double cropping of winter wheat and summer maize sustains a high production of cereal grains, but the system relies heavily on artificial fertilizer and ...

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    Decoding tropical forest change at fine scale with multi-sensor satellite data and artificial intelligence
    Slagter, Bart2026
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  • Tropical forests are of crucial importance but are seriously threatened by human-driven deforestation and forest degradation. To better manage and protect tropical forests, we need fast and precise satellite-derived information on forest change, its causes, and its impacts. Current remote sensing-based monitoring systems commonly focus on generic detections of tree cover loss only, without thematic distinction of direct drivers, and often have a critical blind spot for selective logging act ...

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    Global multi-pollutant modelling: uncovering new perspectives for river exports of nutrients, plastics, and chemicals
    Micella, Ilaria2026
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  • This thesis assesses river exports of nutrients, plastics, and chemicals to coastal waters worldwide across sub-basins in the 21st century under socio-economic disparities and climate-driven hydrological changes. Using the new MARINA-Multi model, results show that in 2010, diffuse sources contributed by >95% to river exports of nitrogen and macroplastics, while point sources contributed by about 40% to river exports of phosphorus and microplastics globally. Future multi-pollutant scenarios ...

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    Disease suppression in intercropping systems: a mechanistic perspective
    Homulle, Zohralyn2026
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  • The mechanisation, specialisation and intensification of agriculture have resulted in highly efficient and productive agricultural systems. However, this mode of agriculture also comes at a cost; it contributes to numerous forms of environmental degradation, biodiversity loss, and land and water pollution. Monocultures - (large-scale) fields where a single crop type is grown - are a key element of such agricultural systems, and relatively vulnerable to pests and diseases. Intercropping, the ...

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    Finding the Achilles’ heel of Streptococcus suis : molecular mechanisms of adaptation to host-like environments
    Juanpere-Borràs, Maria2026
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  • This thesis investigates how Streptococcus suis adapts to host environments and identifies vulnerabilities that could inform new antimicrobial strategies. Using transposon mutagenesis and host-derived fluids, we uncovered conditionally essential genes that support growth in activated porcine serum and cerebrospinal fluid, highlighting key roles for purine biosynthesis, membrane homeostasis, and amino acid transport. We then dissected membrane-stress responses and revealed a coordinated regu ...

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    Towards understanding uncertainties in the measurement of microplastic concentrations in river systems
    Wang, Siting2026
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  • This thesis investigates how methodological choices and regional context shape freshwater microplastic monitoring and risk assessment. It first evaluates key analytical parameters, showing that higher-resolution micro-FTIR objectives greatly increase detected particle numbers, while a 20 micro-m sieve can be sufficient for routine work. It then quantifies abundances, size spectra and polymer types in the Yangtze–Huangpu system and the Rhine–Meuse delta, revealing high contamination and regi ...

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    Beyond land restoration: learning from successful smallholder communities
    Asresehegn, Tewodros G.2026
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  • Land degradation remains a pervasive global challenge, undermining ecosystem functions and threatening rural livelihoods. Its impacts are particularly severe for smallholder farmers, who account for nearly one-third of global food production and provide the primary source of food calories in many low-income countries. Addressing both the current and anticipated land degradation is therefore not only a local imperative but also a global priority, situating land restoration at the core of sus ...

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    Species sorting and community-level functionality in a natural microbial community: experiments using a traditional fermented dairy ecosystem model from Zambia
    Nehanda, Shepherd2026
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  • Microbial communities are continuously faced with environmental changes, leading to unpredictable states in their structure and functioning. Species sorting has been one of the important concepts pursued to understand the microbial community assembly process, which views member species as being driven by their differential fitness traits in response to selection. Several model systems have been applied regarding the study of species sorting, yet the complexity of field-based models often at ...

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    Nudges, integrated pest management, and livelihoods : experimental evidence from rural Ethiopia
    Deffersha, Solomon Balew2026
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  • The thesis looks at how small changes in how we present information or rewards can help farmers and communities adopt better farming and health practices. I focused on rural Ethiopia, studying ways to encourage farmers to use new technologies that can boost crop yields and reduce pests, as well as ways to prevent malaria through house improvements. I found that using social recognition and highlighting risks of not acting (loss framing) are powerful tools to motivate change. These small nud ...

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    Application of trait-based plant-soil feedback for agroecosystem optimization
    Bin, Zhaoqi2026
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  • The Green Revolution increased global food production, but intensive agriculture now relies heavily on fertilizers and pesticides, resulting in soil degradation, pollution, resource depletion, and biodiversity loss. Sustainable agriculture therefore requires not only maintaining crop yields but also supporting multiple soil functions, such as biomass production, nutrient cycling, carbon storage, and disease suppressiveness, simultaneously, a concept known as soil multifunctionality. These f ...

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    Inclusive business beyond borders: the role of innovation intermediaries in market integration for the Base-of-the-Pyramid
    Danse, Myrtille G.2026
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  • This dissertation examines how business models aimed at improving food security in Base-of-the-Pyramid (BOP) markets can be effectively developed and socially embedded to generate mutual economic and social value. Addressing a central dilemma in international development, the study examines how multinational enterprises (MNEs) pursue commercial objectives while contributing to social outcomes in contexts characterized by poverty, institutional voids, and fragmented value chains. The researc ...

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    Assessment of micro and nanoplastic toxicity and their protein corona using in vitro and in silico new approach methodologies
    Brouwer, Hugo2026
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  • The invention of plastic has revolutionized our world by providing a readily available,---moldable material which is light, strong and durable. However, excessive use of plastics has led to universal pollution of our planet. Over time plastic waste and products---can degrade, leading to release of microscopic particles called microplastics and---nanoplastics(MNPs). MNPs are abundant in our food, the water we drink and the air we---breathe and in turn human exposure is unavoidable. Oral inge ...

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    Microalga as a sustainable oil crop
    Abdelkarim, Omnia H.2026
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  • Microalgae represent promising sustainable platforms for producing high-value lipid compounds, yet our understanding of how environmental factors regulate carbon partitioning between fatty acid and sterol biosynthesis remains limited. This thesis investigates how nitrogen availability, light intensity, temperature, and salinity affect carbon allocation between fatty acid and sterol across multiple microalgal species, with particular focus on Nannochloropsis oceanica.---Our research revealed ...

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    The fate and removal of micropollutants and antibiotic resistance in aerobic granular sludge systems
    Feng, Zhaolu2026
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  • Emerging contaminants, including micropollutants (OMPs), antibiotic resistant bacteria (ARB), and their genes (ARGs), are frequently detected in municipal wastewater and are only partially removed by conventional activated sludge systems. Aerobic granular sludge (AGS) process offers a promising alternative, but its granule size distribution and batch-fed operation lead to different treatment dynamics. To date, the fate and removal of these contaminants in full-scale AGS systems, especially ...

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    Envisage phenotyping : integrating artificial intelligence in image analysis for selective breeding in aquaculture
    Xue, Yuanxu2026
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  • Automated phenotyping is a rapidly evolving interdisciplinary field focused on high-throughput, non-invasive phenotype collection to support breeding and management decisions in aquaculture. Current development primarily targets production traits, leaving a gap in traits linked with metabolism, health and physiological well-being. These traits are complex and difficult to measure, but advancements in AI-based prediction models combined with imaging technologies provide opportunities. This t ...

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    Towards a sustainable food system in China: insights from an integrated environmental-economic modelling approach
    Long, Weitong2026
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  • Feeding a growing global population in a healthy manner while reducing environmental degradation is one of the most pressing challenges of the 21st century. Addressing this challenge calls for a transition from the current food system towards a system that is not only resilient but also equitable and environmentally sustainable. Although numerous studies have examined the environmental benefits of various food system transformation options, many of them neglect the economic interactions. Us ...

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    Machine learning for fertilizer recommendation in Ghana
    Asamoah, Eric2026
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  • Maize is a major staple crop in Ghana and across Sub-Saharan Africa (SSA), yet yields remain far below their potential due to persistent soil fertility constraints, inefficient fertilizer use, and reliance on blanket recommendations that fail to capture site-specific variability. Mechanistic models such as QUEFTS have advanced understanding of crop–nutrient relationships, but their application in SSA is limited by high data requirements and weak consideration of farmer risk and socioeconomi ...

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