Record nummer 1912452
Titel Relative oral bioavailability of lead from Dutch made grounds
toon extra info.
W.I. Hagens ... [et al.]
Auteur(s) Hagens, W.I.
Uitgever Bilthoven : RIVM
Jaar van uitgave cop. 2009
Pagina's 137 p + bijl. (63 p.) ill
Titel van reeks RIVM report / National Institute for Public Health and the Environment (711701086/2009)
Annotatie(s) This investigation has been performed by order and for the account of the Ministery of Housing, Spatial Planning and the Environment (VROM), DGM-DP and DGR-LOK, within the framework of project M/711701/BE, Risico's in relatie tot bodemkwaliteit/Implementatie biobeschikbaarheid mens
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Trefwoorden (cab) bodemverontreiniging / lood / toxicologie / risicoschatting / modellen / monitoring / ecotoxicologie
Rubrieken Bodemverontreiniging
Publicatie type Boek
Taal Engels
Toelichting (Engels) The soil in the historical inner (city) areas of many Dutch cities and villages is often polluted with lead. This lead originates from several sources, including the accumulation of lead-containing waste products and building rubble associated with centuries of urban development and industrial activities. Made grounds from different sources appear to have rather uniform soil characteristics, despite differences in the original soil lithology (clay, sand, loess). Possibly because of this uniformity, no relation has been observed between the release of lead from made grounds and soil characteristics. Results obtained using the in vitro digestion model IVD model (RIVM), however, do indicate a qualitative relation between lead mineralogy and the release of lead from made grounds. The results of prior comparisons of the IVD and Tiny-TIM (TNO) models using human and animal data are in close agreement. To obtain a definitive answer on the usability of these models in risk assessment, however, the RIVM recommends that additional validation tests be run using relevant human or animal data
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