De Novo Acquisition of Resistance to Three 1 Antibiotics by 2 Escherichia coli
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Michael A. van der Horst ... [et al.]
|Auteur(s)||Horst, M.A. van der|
|Amsterdam [etc.] : University of Amsterdam, Laboratory for Molecular Biology and Microbial Food Safety [etc.]|
|Trefwoorden (cab)||escherichia coli / antibiotica / antibioticaresistentie / gezondheid|
|Toelichting (Engels)||In this study the authors describe the de novo acquisition of resistance by E. coli against three antibiotics, the bactericidals amoxicillin and enrofloxacin and the bacteriostatic tetracycline. The metabolic costs of the resistance in each of these cases are compared. All data considered together suggest that the greatest risk of acquired resistance results from exposure to sub-MIC (minimal inhibitory concentration) concentrations of antibiotics.|