Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 328161
Title Tris(4-chlorophenyl) methanol and tris(4-chlorophenyl) methane
Author(s) Boer, J. de
Source In: The Handbook of Environmental Chemistry / Hutziner, O., Paasivirta, J., Heidelberg : Springer - ISBN 9783540658382 - p. 31 - 41.
Department(s) Netherlands Institute for Fisheries Research
Publication type Chapter in scientific book
Publication year 2000
Abstract Tris(4-chlorophenyl)methanol (TCPM) and tris(4-chlorophenyl)methane (TCPMe) are globally widespread contaminants. However, there is a lack of knowledge on production figures, origin, and application of these compounds. One source is technical DDT in which these compounds are present as impurities, but it is assumed that there are other sources as well. Analytical methods for the determination of TCPM and TCPMe comprise extraction, cleanup over florisil columns or by gel permeation chromatography, and gas chromatographic analysis with electron capture or mass spectrometric detection. TCPM and TCPMe have been found in fish, birds, and marine mammals from various parts of the world. TCPM concentrations in marine mammals from the North Sea are around 1-2 mg/kg on a lipid weight basis. TCPM and TCPMe are highly bioaccumulative and a 10-100-fold biomagnification from fish to marine mammals is suggested. There is little information on their toxicity. TCPM is a phenobarbital and a 3-methylcholanthrene inducer producing hepatic effects, splenomegaly, and increased white blood cell and lymphocyte counts in rats after short-term dietary exposure. There are indications of a possible carcinogenic character.
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