Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 334002
Title Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut functionality
Author(s) Vos, W.M. de; Bron, P.A.; Kleerebezem, M.
Source Current Opinion in Biotechnology 15 (2004)2. - ISSN 0958-1669 - p. 86 - 93.
Department(s) Microbiology
Publication type Refereed Article in a scientific journal
Publication year 2004
Keyword(s) human gastrointestinal-tract - signature-tagged mutagenesis - vivo expression technology - escherichia-coli k-12 - listeria-monocytogenes - lactococcus-lactis - stress resistance - in-vivo - propionibacterium-freudenreichii - lactobacillus-reuteri
Abstract Recent years have seen an explosion in the number of complete or almost complete genomic sequences of lactic acid bacteria and other food-grade bacteria that are used in functional foods to increase the health of the consumer. These have been instrumental in the development of functional, comparative and other post-genomics approaches that provide the possibility to detect, unravel and understand their functionality in the human intestinal tract. In conjunction with other high-throughput approaches, these advances can be exploited in the functional food innovation cycle for developing new or designed probiotic and other bacterial products that impact gut health.
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