Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 335043
Title Potential of metabolomics as a functional genomics tool
Author(s) Bino, R.J.; Hall, R.D.; Fiehn, O.; Kopka, J.; Saito, K.; Draper, J.; Nikolau, B.J.; Mendes, P.; Roessner-Tunali, U.; Beale, M.; Trethewey, R.N.; Lange, B.M.; Wurtele, E.S.; Sumner, L.W.
Source Trends in Plant Science 9 (2004)9. - ISSN 1360-1385 - p. 418 - 424.
Department(s) Laboratory of Plant Physiology
PRI Bioscience
Publication type Refereed Article in a scientific journal
Publication year 2004
Keyword(s) mass-spectrometry - systems biology - secondary metabolites - arabidopsis-thaliana - plant metabolomics - potato-tuber - database - chromatography - information - proteomics
Abstract Metabolomics is developing as an important functional genomics tool; however, there is still room for technical improvements in both the large-scale determination of metabolites from complex plant tissues and the dissemination of metabolomics research data. For the continued maturation of metabolomics, the following three objectives need to be achieved: (i) improvement in the comprehensive coverage of the plant metabolome, (ii) facilitation of comparison of results between laboratories and experiments, and (iii) enhancement of the integration of metabolomic data with other functional genomic information. Because these challenges are widely recognized and endorsed, we propose community-based efforts to define common criteria and to initiate concerted actions directed towards the release of standard reference materials, construction of consolidated metabolite libraries, and development of metabolite-specific data-management systems.
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