Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 352412
Title Horizontal transmission experiment of paratuberculosis
Author(s) Roermund, H.J.W. van; Jong, M.C.M. de
Source In: Proceedings 8th International Colloquium on Paratuberculosis, Copenhagen, Denmark, 14-18 August 2005. - - p. 672 - 678.
Event 8th International Colloquium on Paratuberculosis, Copenhagen, Denmark, 2005-08-14/2005-08-18
Department(s) ID - Infectieziekten
Quantitative Veterinary Epidemiology
WIAS
Publication type Contribution in proceedings
Publication year 2005
Abstract In September 2001 two groups of 5 calves were placed between two groups of 6 infectious cows in a row during 3 months (Period 1). Calves were one week old at the start and born in MAP-unsuspected status-10 herds. Cows were artificially (orally) infected at one month of age in Januari 1999. Each calf was housed in an open box (to avoid injuries) between two cows, and their position in the row was randomly changed every two weeks. Calves were not artificially infected by us. During a second period of 3 months, each group of 5 calves was housed together with 5 new calves (one week old at the start) in a separate group-stable (Period 2). Every two weeks in Period 1 and 2 blood and faecal samples were taken of all animals. After this period, the 20 calves were transferred to a farm (only crops, no other animals) and housed in a row with dividing walls to avoid direct or faecal contact (until summer 2005). Every two months blood and faecal samples were taken of all 20 animals. In autumn 2004 the animals were inseminated.Results of test-positive animals will be shown. Horizontal cow-calf transmission seems to be easy (Period 1). At the highest infection pressure (6 shedding cows of which 3 continuously in Period 1) all calves excreted MAP in their faeces during Period 1 (shortly after infection), and also during Period 2 (when the shedding cows were absent). After that, excretion declined. Horizontal calf-calf transmission did take place (Period 2). The transmission rate (reproduction ratio R0) will be quantified at the end of the experiment, because more animals can still become faecal-culture positive, especially shortly before calving (summer 2005)
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