Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 357207
Title Hydrodynamic flow caused by active transport along cytoskeletal elements
Author(s) Houtman, D.; Pagonabarraga, I.; Lowe, C.P.; Esseling-Ozdoba, A.; Emons, A.M.C.; Eiser, E.
Source Europhysics Letters 78 (2007)1. - ISSN 0295-5075 - p. 1 - 5.
DOI https://doi.org/10.1209/0295-5075/78/18001
Department(s) Laboratory of Cell Biology
EPS-1
Publication type Refereed Article in a scientific journal
Publication year 2007
Keyword(s) molecular motors
Abstract We develop a simple lattice model to describe the hydrodynamic influence of active mass transport along bio-filaments on freely diffusing mass in the cell. To quantify the overall mass transport we include Brownian motion, excluded volume interactions, active transport along the filaments, and hydrodynamic interactions. The model shows that the hydrodynamic forces induced by molecular motors attached to the filaments give rise to a non-negligible flux close to the filament. This additional flux appears to have two effects. Depending on the degree of filament occupation it can exert a sufficiently large influence on unbound motors and cargo to modify their transport and also regulate the flux of motors bound to the filament. We expect such a mechanism is important in situations found in plant cells, where directional transport spans the entire cell. In particular, it can explain the cytoplasmic streaming observed in plant cells.
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