Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 384038
Title Intakes of (n-3) Fatty Acids and Fatty Fish Are Not Associated with Cognitive Performance and 6-Year Cognitive Change in Men Participating in the Veterans Affairs Normative Aging Study
Author(s) Rest, O. van de; Spiro, A.; Krall-Kaye, E.; Geleijnse, J.M.; Groot, C.P.G.M. de; Tucker, K.L.
Source The Journal of Nutrition 139 (2009)12. - ISSN 0022-3166 - p. 2329 - 2336.
DOI https://doi.org/10.3945/jn.109.113647
Department(s) Global Nutrition
Nutrition and Disease
Human Nutrition & Health
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2009
Keyword(s) food frequency questionnaire - erythrocyte-membranes - alzheimers-disease - older-adults - plasma - decline - health - homocysteine - population - risk
Abstract High intake of fish and (n-3) PUFA may protect against age-related cognitive decline. However, results are inconsistent and limited data exist regarding changes in multiple cognitive functions over a longer period of time. In this study, we assessed the association between fatty fish intake as well as (n-3) PUFA intake with cognitive performance and cognitive change over 6 y in 1025 elderly men. Participants were from the Veterans Affairs Normative Aging Study. Cognitive function was assessed with a battery of cognitive tests focusing on factors representing memory/language, speed, and visuospatial/attention. Dietary intakes were assessed with a validated FFQ. We used general linear models to assess cross-sectional associations and mixed models to assess the associations over time. Models were adjusted for age, education, BMI, smoking, diabetes, and intake of alcohol, saturated fat, vitamin C, and vitamin E. The mean age of participating men was 68 y at baseline. Median fish consumption ranged from 0.2 to 4.2 servings/wk across quartiles. Cross-sectional analyses showed no association between fatty fish or (n-3) PUFA intake and cognitive performance. Longitudinal analyses, over 6 y of follow-up, also did not show any significant associations between fatty fish or (n-3) PUFA intake and cognitive change. In this population of elderly men, intake of neither fatty fish nor (n-3) PUFA was associated with cognitive performance
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