Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 395715
Title Detection and use of QTL for complex traits in multiple environments.
Author(s) Eeuwijk, F.A. van; Bink, M.C.A.M.; Chenu, K.; Chapman, S.C.
Source Current Opinion in Plant Biology 13 (2010)2. - ISSN 1369-5266 - p. 193 - 205.
DOI https://doi.org/10.1016/j.pbi.2010.01.001
Department(s) Mathematical and Statistical Methods - Biometris
Biometris
PE&RC
Publication type Refereed Article in a scientific journal
Publication year 2010
Keyword(s) model selection approach - chain monte-carlo - mixed-model - water-deficit - leaf growth - experimental crosses - quantitative traits - plant-populations - breeding program - flanking markers
Abstract QTL mapping methods for complex traits are challenged by new developments in marker technology, phenotyping platforms, and breeding methods. In meeting these challenges, QTL mapping approaches will need to also acknowledge the central roles of QTL by environment interactions (QEI) and QTL by trait interactions in the expression of complex traits like yield. This paper presents an overview of mixed model QTL methodology that is suitable for many types of populations and that allows predictive modeling of QEI, both for environmental and developmental gradients. Attention is also given to multi-trait QTL models which are essential to interpret the genetic basis of trait correlations. Biophysical (crop growth) model simulations are proposed as a complement to statistical QTL mapping for the interpretation of the nature of QEI and to investigate better methods for the dissection of complex traits into component traits and their genetic controls
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