Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 397844
Title Genomic Selection, a Revolution in Dairy Cattle Breeding
Author(s) Veerkamp, R.F.
Event 14th Annual Conference of The European Society for Domestic Animal Reproduction (ESDAR), Eger, Hungary, 2010-09-14/2010-09-18
Department(s) Research
Publication type Abstract in scientific journal or proceedings
Publication year 2010
Abstract The introduction of genomic selection appears one of the biggest revolutions in dairy cattle breeding over the past two decades. Initially the impact of genomic information was limited in breeding programs. This was because the search for genetic markers that were linked to quantitative trait loci (QTL) proved to be costly and cumbersome. Several QTL were found but most of them explained only a relatively small part of the genetic variation. Also, it appeared difficult to find the causal mutation causing the effects. Genomic selection pays no attention to the effects of a single marker, but combines the effects of many markers spread across the whole genome instead. Genotyping many markers has become very practical since genotyping costs have decreased drastically. The costs of genotyping ten or hundreds of thousands SNPs on an individual animal has reduced to a few hundred Euro’s, and is likely to become even cheaper in the near future. Therefore, there is no need to find the few most important QTL anymore. Meanwhile, statistical methods have been developed to estimate the effects of all these SNPs together in a reference population, and to predict breeding values for the genotyped selection candidates. Early on simulations studies promised that accurate selection was possible using these genomic breeding values. These results have been backed up by cross validation studies and the first daughters milking. Genomic selection gives breeding organizations the option to select animals at a very young age, with a relatively high accuracy. It is predicted to save up to 90% of the costs of a breeding program.
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