Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 407829
Title Bioinformatics tools and database resources for systems genetics analysis in miceça short review and an evaluation of future needs
Author(s) Durrant, M.C.; Swertz, M.A.; Alberts, R.; Arends, D.; Möller, S.; Mott, R.; Prins, J.C.P.; Velde, K.J. van der; Jansen, R.C.; Schughart, K.
Source Briefings in Bioinformatics 13 (2012)2. - ISSN 1467-5463 - p. 135 - 142.
Department(s) Laboratory of Nematology
PRI Biometris
Publication type Refereed Article in a scientific journal
Publication year 2012
Keyword(s) quantitative trait loci - collaborative cross - powerful resource - complex - atherosclerosis - genomics - biology - genes - r/qtl - men
Abstract During a meeting of the SYSGENET working group ‘Bioinformatics’, currently available software tools and databases for systems genetics in mice were reviewed and the needs for future developments discussed. The group evaluated interoperability and performed initial feasibility studies. To aid future compatibility of software and exchange of already developed software modules, a strong recommendation was made by the group to integrate HAPPY and R/qtl analysis toolboxes, GeneNetwork and XGAP database platforms, and TIQS and xQTL processing platforms. R should be used as the principal computer language for QTL data analysis in all platforms and a ‘cloud’ should be used for software dissemination to the community. Furthermore, the working group recommended that all data models and software source code should be made visible in public repositories to allow a coordinated effort on the use of common data structures and file formats.
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