Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 445291
Title The immunomodulatory nutritional intervention NR100157 reduced CD4+ T-Cell decline and immune activation: a 1-year multicenter randomized controlled double-blind trial in HIV-infected persons not receiving antiretroviral therapy (The BITE Study)
Author(s) Cahn, P.; Ruxrungtham, K.; Gazzard, B.; Norren, K. van; Diaz, R.S.; Gori, A.; Kotler, D.P.; Vriesema, A.; Georgiou, N.A.; Garssen, J.; Clerici, M.; Lange, J.M.A.
Source Clinical infectious diseases 57 (2013)1. - ISSN 1058-4838 - p. 139 - 146.
Department(s) Nutritional Biology and Health
Publication type Refereed Article in a scientific journal
Publication year 2013
Keyword(s) virus type-1 infection - viral load - bovine colostrum - pathogenesis - restoration - enteropathy - prebiotics - depletion - survival - mucosa
Abstract Background The immunomodulatory nutritional product NR100157 was developed for human immunodeficiency virus (HIV)–infected individuals. We hypothesized that targeting the compromised gastrointestinal tract of HIV-infected individuals would result in systemic immunological benefits. Methods In a multicenter, randomized, controlled, double-blind trial, 340 HIV-1–positive adults not on antiretroviral therapy, with CD4+ T-cell counts
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