Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 448366
Title Spatial coordination between stem cell activity and cell differentiation in the root meristem
Author(s) Moubayidin, L.; Mambro, R. Di; Sozzani, R.; Pacifici, E.; Salvi, E.; Terpstra, I.; Bao, D.; Dijken, A. van; Dello loio, R.; Perilli, S.; Ljung, K.; Benfey, P.N.; Heidstra, R.; Costantino, P.; Sabatini, S.
Source Developmental Cell 26 (2013)4. - ISSN 1534-5807 - p. 405 - 415.
DOI https://doi.org/10.1016/j.devcel.2013.06.025
Department(s) Plant Developmental Biology
Publication type Refereed Article in a scientific journal
Publication year 2013
Keyword(s) gras gene family - arabidopsis root - auxin biosynthesis - scarecrow - expression - thaliana - transport - division - growth - niche
Abstract A critical issue in development is the coordination of the activity of stem cell niches with differentiation of their progeny to ensure coherent organ growth. In the plant root, these processes take place at opposite ends of the meristem and must be coordinated with each other at a distance. Here, we show that in Arabidopsis, the gene SCR presides over this spatial coordination. In the organizing center of the root stem cell niche, SCR directly represses the expression of the cytokinin-response transcription factor ARR1, which promotes cell differentiation, controlling auxin production via the ASB1 gene and sustaining stem cell activity. This allows SCR to regulate, via auxin, the level of ARR1 expression in the transition zone where the stem cell progeny leaves the meristem, thus controlling the rate of differentiation. In this way, SCR simultaneously controls stem cell division and differentiation, ensuring coherent root growth.
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