Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 480014
Title Evolutionary engineering to enhance starter culture performance in food fermentations
Author(s) Bachmann, H.; Pronk, J.T.; Kleerebezem, M.; Teusink, B.
Source Current Opinion in Biotechnology 32 (2015). - ISSN 0958-1669 - p. 1 - 7.
DOI https://doi.org/10.1016/j.copbio.2014.09.003
Department(s) Microbiology
Host-Microbe Interactomics
WIAS
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) yeast saccharomyces-cerevisiae - adaptive evolution - lactococcus-lactis - hyperosmotic conditions - selection - growth - population - strategies - phenotypes - stability
Abstract Microbial starter cultures are essential for consistent product quality and functional properties such as flavor, texture, pH or the alcohol content of various fermented foods. Strain improvement programs to achieve desired properties in starter cultures are diverse, but developments in next-generation sequencing lead to an increased interest in evolutionary engineering of desired phenotypes. We here discuss recent developments of strain selection protocols and how computational approaches can assist such experimental design. Furthermore the analysis of evolved phenotypes and possibilities with complex consortia are highlighted. Studies carried out with mainly yeast and lactic acid bacteria demonstrate the power of evolutionary engineering to deliver strains with novel phenotypes as well as insight into underlying mechanisms.
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