Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 480981
Title Binning metagenomic contigs by coverage and composition
Author(s) Alneberg, J.; Bjarnason, B.S.; Bruijn, I. de; Schirmer, M.; Quick, J.; Ijaz, U.Z.; Lahti, L.M.; Loman, N.J.; Andersson, A.F.; Quince, C.
Source Nature Methods : techniques for life scientists and chemists 11 (2014). - ISSN 1548-7091 - p. 1144 - 1146.
DOI https://doi.org/10.1038/nmeth.3103
Department(s) Microbiology
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2014
Keyword(s) sequences - genomes
Abstract Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but because assembly does not reconstruct entire genomes, it is necessary to bin genome fragments. Here we present CONCOCT, a new algorithm that combines sequence composition and coverage across multiple samples, to automatically cluster contigs into genomes. We demonstrate high recall and precision on artificial as well as real human gut metagenome data sets.
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