Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 482551
Title Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women
Author(s) Mwangi, M.N.; Maskey, S.; Andang'o, P.E.A.; Shinali, N.K.; Roth, J.M.; Trijsburg, L.; Mwangi, A.M.; Zuilhof, H.; Lagen, B. van; Savelkoul, H.F.J.; Demir, Ayse Y.; Verhoef, J.C.M.
Source BMC Medicine 12 (2014). - ISSN 1741-7015
Department(s) Cell Biology and Immunology
Global Nutrition
Nutrition and Disease
Organic Chemistry
Human Nutrition & Health
Publication type Refereed Article in a scientific journal
Publication year 2014
Keyword(s) erythrocyte protoporphyrin - increased erythropoiesis - lactate-dehydrogenase - asymptomatic malaria - serum ferritin - children - anemia - hemoglobin - alpha(+)-thalassemia - hematofluorometry
Abstract Iron-deficient erythropoiesis results in excess formation of zinc protoporphyrin (ZPP), which can be measured instantly and at low assay cost using portable haematofluorometers. ZPP is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration. We examined associations between ZPP and disorders that are common in Africa. In addition, we assessed the diagnostic utility of ZPP (measured in whole blood and erythrocytes), alone or in combination with haemoglobin concentration, in detecting iron deficiency (plasma ferritin concentration
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