Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 488697
Title Current issues involving screening and identification of chemical contaminants in foods by mass spectrometry
Author(s) Lehotay, S.J.; Sapozhnikova, Y.; Mol, J.G.J.
Source TrAC : Trends in Analytical Chemistry 69 (2015). - ISSN 0165-9936 - p. 62 - 75.
DOI https://doi.org/10.1016/j.trac.2015.02.012
Department(s) BU Contaminants & Toxins
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) performance liquid-chromatography - pesticide-residue analysis - ion mobility spectrometry - information-dependent acquisition - pressure desorption ionization - supersonic molecular-beams - veterinary drug residues - flow-injection analysis - gas-chromatography
Abstract Although quantitative analytical methods must be empirically validated prior to their use in a variety of applications, including regulatory monitoring of chemical adulterants in foods, validation of qualitative method performance for the analytes and matrices of interest is frequently ignored, or general guidelines are assumed to be true for specific situations. Just as in the case of quantitative method validation, acceptable method performance criteria should be established for qualitative analysis purposes to suit the analytical needs for given applications, and empirical method validation should be conducted to demonstrate the qualitative performance capabilities the method. This critical review article is intended to describe and discuss recent developments with of respect to qualitative aspects in mass spectrometry, and to make recommendations for validation of qualitative methods that meet common needs for monitoring of chemical contaminants in foods.
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