Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 489121
Title Equivalent pathways in melding and gelation of well-defined biopolymer networks
Author(s) Cingil, E.H.; Rombouts, W.H.; Gucht, J. van der; Cohen Stuart, M.A.; Sprakel, J.H.B.
Source Biomacromolecules 16 (2015)1. - ISSN 1525-7797 - p. 304 - 310.
Department(s) Physical Chemistry and Soft Matter
Physical Chemistry and Colloid Science
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) multiple-particle tracking - actin filament networks - microheterogeneity - copolymers - hydrogels
Abstract We use multiple particle tracking microrheology to study the melting and gelation behavior of well-defined collagen-inspired designer biopolymers expressed by the transgenic yeast P. Pastoris. The system consists of a hydrophilic random coil-like middle block and collagen-like end block. Upon cooling, the end blocks assemble into well-defined transient nodes with exclusively 3-fold functionality. We apply the method of time-cure superposition of the mean-square displacement of tracer beads embedded in the biopolymer matrix to study the kinetics and thermodynamics of approaching the gel point from both the liquid and the solid side. The melting point, gel point, and critical relaxation exponents are determined from the shift factors of the mean-square displacement and we discuss the use of dynamic scaling exponents to correctly determine the critical transition. Critical relaxation exponents obtained for different concentrations in both systems are compared with the currently existing dynamic models in literature. In our study, we find that, while the time scales of gelation and melting are different by orders of magnitude, and show inverse dependence on concentration, that the pathways followed are completely equivalent.
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