|Title||Integrated Product Recovery Will Boost Industrial Cyanobacterial Processes|
|Author(s)||Berg, Corjan van den; Eppink, Michel H.M.; Wijffels, Rene H.|
|Source||Trends in Biotechnology 37 (2019)5. - ISSN 0167-7799 - p. 454 - 463.|
|Publication type||Refereed Article in a scientific journal|
|Keyword(s)||cyanobacteria - process integration - product recovery - separation|
Cyanobacteria promise to be an important industrial platform for the production of a variety of biobased products such as fuels, plastics, and isoprenoids. Recent advances in synthetic biology have resulted in various cyanobacterial strain improvements. Nevertheless, these new strains are still hampered by product inhibition, resulting in low volumetric productivities, product concentrations, and yields on light. To circumvent these issues, continuous product recovery will need to be applied, resulting in economically viable industrial processes. Optimal product recovery strategies can be developed by considering biological and separation process constraints as well as photobioreactor design. Integrated product recovery will be indispensable to bring the cyanobacterial cell factory to industrial scale.