Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 546188
Title Delivery of genome editing tools by bacterial extracellular vesicles
Author(s) Liu, Yue; Smid, Eddy J.; Abee, Tjakko; Notebaart, Richard A.
Source Microbial Biotechnology 12 (2019)1. - ISSN 1751-7907 - p. 71 - 73.
Department(s) Food Microbiology
Publication type Refereed Article in a scientific journal
Publication year 2019
Abstract Here we propose to use bacterial cells as factories that generate EVs harboring both the RNP complex (or any other CRISPR‐mediated tool) and a specific ligand molecule. The ligand would allow specific binding of EVs to cells with the matching receptors, adding a level of specificity to the delivery, hence stimulating precise genome editing.
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