Arsenic (As) is a naturally occurring element in the Earth’s crust. Both anthropogenic and natural processes can release As into sources for drinking water supply. A substantial epidemiological evidence is available to support that the chronic exposure to high concentrations in drinking water (> 10 μg/L) is associated with several detrimental effects on human health including skin lesions  and cancer of the lung , bladder , kidney , and liver . Furthermore, dermatological, developmental, neurological , respiratory , cardiovascular , immunological , and endocrine effects  as a result of chronic exposure to high As concentrations have been reported. However, there remains considerable uncertainty on the chronic risks due to As exposure at low concentrations (< 10 μg/L) and the shape of the dose-response relationship [10, 11]. It is therefore crucial to question whether the 10 μg/L limit ensures protection of human health from the adverse health effects of As.
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