Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 547842
Title The association between apathy, decline in physical performance, and falls in older persons
Author(s) Henstra, Marieke J.; Rhebergen, Didi; Stek, Max L.; Swart, Karin M.A.; Dijk, Suzanne C. van; Zillikens, M.C.; Oliai Araghi, Sadaf; Groot, Lisette C.M.G.M. de; Schoor, Natasja M. van; Velde, Nathalie van der
Source Aging clinical and experimental research 31 (2019)10. - ISSN 1594-0667 - p. 1491 - 1499.
DOI https://doi.org/10.1007/s40520-018-1096-5
Department(s) VLAG
Global Nutrition
Publication type Refereed Article in a scientific journal
Publication year 2019
Keyword(s) Apathy - Community-dwelling - Fall risk factor - Older persons - Physical performance
Abstract

Background: Symptoms of apathy are common in older persons. Negative effects on physical performance and fall risk are plausible, considering the pathophysiology of apathy. However, literature is scarce. Aim: To longitudinally assess the association between apathy and (1) decline of physical performance and (2) the number of falls in older community-dwelling persons. Methods: The ‘B vitamins for the PRevention Of Osteoporotic Fractures’ study provided data on 2919 older persons over a period of 2 years. Apathy was assessed using the Geriatric Depression Scale 3. A physical performance score (PPS) was calculated using three performance tests. Falls were registered prospectively. We calculated adjusted odds ratios (ORs), Incidence Rate Ratios (IRRs), and their 95% confidence intervals. Effect modification by age and gender was investigated. We also investigated mediation by baseline PPS for the association between apathy and the number of falls. Results: Apathy and decline of PPS were independently associated. After stratification, the effect only remained in men. Age was an effect modifier; higher ORs for decreasing age. Apathy was also independently associated with the number of falls. After stratification, women had higher IRRs than men. Age modified the association in the opposite direction: higher IRRs for increasing age. Baseline PPS was a mediator in the association. Conclusion: The impact of apathy on physical performance and fall incidents varied with age and gender. Potentially, in older individuals with apathy, fall risk is preceded by a decline in physical performance. In clinical practice, identifying apathy in older persons might be useful to target mobility preserving interventions.

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