Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 549407
Title 16S rRNA (gene) based barcoded Illumina sequencing of the microbiota in ileal and colonic luminal content of Ercc1-/Δ7 mice after 10 weeks of Akkermansia muciniphila supplementation
Author(s) Lugt, B.M. van der; Beek, Adriaan A. van; Aalvink, S.; Meijer, B.; Sovran, B.; Vermeij, Wilbert P.; Brandt, Renata M.C.; Vos, W.M. de; Savelkoul, H.F.J.; Steegenga, W.T.; Belzer, C.
Source Wageningen University
Department(s) Nutrition, Metabolism and Genomics
MolEco
Cell Biology and Immunology
Host-Microbe Interactomics
WIMEK
VLAG
Microbiology
WIAS
Publication type Dataset
Publication year 2019
Keyword(s) PRJNA525606 - SRP187521
Abstract The use of Akkermansia muciniphila as potential therapeutic intervention is receiving increasing attention. Health benefits attributed to this bacterium include an improvement of metabolic disorders and exerting anti-inflammatory effects. The abundance of A. muciniphila is associated with a healthy gut in early mid- and later life. However, the effects of A. muciniphila on a decline in intestinal health during the aging process are not investigated yet. We supplemented accelerated aging Ercc1-/Δ7 mice with A. muciniphila for 10 weeks and investigated histological, transcriptional and immunological aspects of intestinal health.
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