|Title||Seeds: A Unique System to Study Translational Regulation|
|Author(s)||Sajeev, Nikita; Bai, Bing; Bentsink, Leónie|
|Source||Trends in Plant Science 24 (2019)6. - ISSN 1360-1385 - p. 487 - 495.|
Laboratory of Plant Physiology
|Publication type||Refereed Article in a scientific journal|
|Keyword(s)||long-lived mRNA - ribosome - seed germination - translational regulation|
Seeds accumulate mRNA during their development and have the ability to store these mRNAs over extended periods of time. On imbibition, seeds transform from a quiescent dry state (no translation) to a fully active metabolic state, and selectively translate subsets of these stored mRNA. Thus, seeds provide a unique developmentally regulated ‘on/off’ switch for translation. Additionally, there is extensive translational control during seed germination. Here we discuss new findings and hypotheses linked to mRNA fate and the role of translational regulation in seeds. Translation is an understated yet important mode of gene regulation. We propose seeds as a novel system to study developmentally and physiologically regulated translation.