Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 551625
Title Honey bee predisposition of resistance to ubiquitous mite infestations
Author(s) Broeckx, Bart J.G.; Smet, Lina De; Blacquière, Tjeerd; Maebe, Kevin; Khalenkow, Mikalaï; Poucke, Mario Van; Dahle, Bjorn; Neumann, Peter; Bach Nguyen, Kim; Smagghe, Guy; Deforce, Dieter; Nieuwerburgh, Filip Van; Peelman, Luc; Graaf, Dirk C. de
Source Scientific Reports 9 (2019)1. - ISSN 2045-2322 - 1 p.
DOI https://doi.org/10.1038/s41598-019-44254-8
Department(s) Biointeractions and Plant Health
Publication type Refereed Article in a scientific journal
Publication year 2019
Abstract

Host-parasite co-evolution history is lacking when parasites switch to novel hosts. This was the case for Western honey bees (Apis mellifera) when the ectoparasitic mite, Varroa destructor, switched hosts from Eastern honey bees (Apis cerana). This mite has since become the most severe biological threat to A. mellifera worldwide. However, some A. mellifera populations are known to survive infestations, largely by suppressing mite population growth. One known mechanism is suppressed mite reproduction (SMR), but the underlying genetics are poorly understood. Here, we take advantage of haploid drones, originating from one queen from the Netherlands that developed Varroa-resistance, whole exome sequencing and elastic-net regression to identify genetic variants associated with SMR in resistant honeybees. An eight variants model predicted 88% of the phenotypes correctly and identified six risk and two protective variants. Reproducing and non-reproducing mites could not be distinguished using DNA microsatellites, which is in agreement with the hypothesis that it is not the parasite but the host that adapted itself. Our results suggest that the brood pheromone-dependent mite oogenesis is disrupted in resistant hosts. The identified genetic markers have a considerable potential to contribute to a sustainable global apiculture.

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