Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 551911
Title The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions
Author(s) Fox, Adam; Bird, J.A.; Fiocchi, Alessandro; Knol, Jan; Meyer, Rosan; Salminen, Seppo; Sitang, Gong; Szajewska, Hania; Papadopoulos, Nikolaos
Source World Allergy Organization Journal 12 (2019)5. - ISSN 1939-4551
DOI https://doi.org/10.1016/j.waojou.2019.100034
Department(s) MolEco
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2019
Keyword(s) Allergy - Anaphylaxis - Bifidobacteria - Cow's milk allergy - Dysbiosis - IgE - Lactobacilli - Microbiota - Prebiotic - Probiotic - Synbiotic - World Allergy Organization
Abstract

Cow's milk allergy is one of the most commonly reported childhood food allergies, with increasing incidence, persistence and severity in many countries across the world. The World Allergy Organization Special Committee on Food Allergy has identified cow's milk allergy as an area in need of a rationale-based approach in order to make progress against what it considered an onerous problem, with worldwide public health impact. There is growing interest in the potential role of the gut microbiota in the early programming and development of immune responses and allergy. This discussion paper considers the rationale and available evidence for modulation of the gut microbiota and for the use of synbiotics in the management of infants at risk of, or living with cow's milk allergy and summarizes remaining research questions that need to be answered for the development of evidence-based recommendations.

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